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Invitrogen
Phospho-MYL2 (Thr18) Recombinant Rabbit Monoclonal Antibody (8X1X2)
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Phospho-MYL2 (Thr18) Antibody (MA5-55181) in WB
Western blot analysis of lysates from HeLa cells, using Phospho-MYL2 (Thr18) Recombinant Monoclonal Antibody (Product # MA5-55181) at 1:1,000 dilution. HeLa cells were treated by Calyculin A (100 nM) at 37&(8)451; for 30 minutes after serum-starvation overnight followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) secondary antibody at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: ... View More
Product Details
MA5-55181
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
8X1X2
Immunogen
A synthetic phosphorylated peptide around T18 of human Myosin Light Chain 2.
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
RRID
AB_3667427
Product Specific Information
Immunogen Sequence: ATSNV
Target Information
Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cardiac myosin light chain 2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC-2; MLC-2s/v; MLC-2v; Myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain phosphatase; myosin light chain-2; Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; Ventricular myosin light chain 2
Gene Aliases: CMH10; MLC-2s/v; MLC2; MYL2
UniProt ID: (Human) P10916
Entrez Gene ID: (Human) 4633
regulation of the force of heart contraction
regulation of striated muscle contraction
heart development
post-embryonic development
muscle filament sliding
negative regulation of cell growth
muscle cell fate specification
muscle fiber development
cardiac myofibril assembly
ventricular cardiac muscle tissue morphogenesis
heart contraction
cardiac muscle contraction
positive regulation of the force of heart contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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