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Invitrogen
Phospho-MYL9/MYL12 (Thr17, Ser18) Polyclonal Antibody
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Product Details
PA5-64483
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MLC-2 (Phospho-Thr17+Ser18)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2662481
Product Specific Information
Phospho-MLC-2 polyclonal antibody detects endogenous levels of MLC-2 (Thr17/Ser18): MLC-2A/MYL12B, MLC-2B/MYL12A, and MLC-2C/MYL9.
Target Information
Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 20 kDa myosin light chain; brain specific myosin regulatory light chain; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC-2; MLC-2A; MLC-2B; MLC-2C; MLC20; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; Myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; Myosin regulatory light chain 20 kDa; myosin regulatory light chain 3; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; Myosin regulatory light chain RLC-A; myosin regulatory light chain-B; Myosin regulatory light polypeptide 9; Myosin RLC; Myosin RLC-A; Myosin RLC-B; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); NMDA receptor-interacting protein; SHUJUN-1
Gene Aliases: 1500001M02Rik; 2900073G15Rik; AI327049; AI838292; C77744; C80200; HEL-S-24; LC20; MLC-2B; MLC-2C; MLC-B; MLC2; MLC20; MLCB; MRCL3; MRLC1; MRLC2; MRLC3; Mrlcb; MYL12A; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; MYRL2; RGD1309537; RLC; Rlc-a; RLC-B; RLC-C
UniProt ID: (Human) P19105, (Human) O14950, (Human) P24844, (Rat) P13832, (Rat) P18666, (Mouse) Q3THE2, (Rat) Q64122, (Mouse) Q9CQ19
Entrez Gene ID: (Human) 10627, (Human) 103910, (Human) 10398, (Rat) 501203, (Mouse) 67268, (Rat) 50685, (Mouse) 67938, (Rat) 296313, (Mouse) 98932
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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