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Invitrogen
Phospho-Naked1 (Ser348) Polyclonal Antibody
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Phospho-Naked1 (Ser348) Antibody (PA5-105097) in WB
Western blot analysis of Phospho-Naked1 (Ser348) in SW480 cell lysate (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-Naked1 (Ser348) polyclonal antibody (Product # PA5-105097).
Product Details
PA5-105097
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NKD1(Accession Q969G9), corresponding to amino acid residues around phosphorylated Ser348.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2816570
Product Specific Information
Antibody detects endogenous levels of NAKED1 only when phosphorylated at Ser348.
Target Information
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin-Tcf signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dvl-binding protein; hNkd; hNkd1; mNkd; mNkd1; naked cuticle 1 homolog; naked cuticle-1; Naked-1; Protein naked cuticle homolog 1
Gene Aliases: 2810434J10Rik; 9030215G15Rik; Naked1; NKD; NKD1; PP7246
UniProt ID: (Human) Q969G9, (Mouse) Q99MH6
Entrez Gene ID: (Human) 85407, (Rat) 364952, (Mouse) 93960
negative regulation of Wnt signaling pathway
positive regulation of protein catabolic process
negative regulation of canonical Wnt signaling pathway
positive regulation of non-canonical Wnt signaling pathway via JNK cascade
negative regulation of convergent extension involved in axis elongation
positive regulation of Wnt signaling pathway, planar cell polarity pathway
multicellular organism development
spermatogenesis
Wnt signaling pathway
cell differentiation
eye photoreceptor cell differentiation
somatic muscle development
regulation of cell motility involved in somitogenic axis elongation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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