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Invitrogen
Phospho-PEA15 (Ser104) Polyclonal Antibody
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Phospho-PEA15 (Ser104) Antibody (PA5-97398) in WB
Western blot analysis of Phospho-PEA15 (Ser104) in extracts of HeLa and C6 cells. Samples were incubated with Phospho-PEA15 (Ser104) Polyclonal antibody (Product # PA5-97398) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. HeLa cells were treated by PMA/TPA (200 nM) for 15 minutes after serum-starvation overnight. C6 cells were treated by... View More
Product Details
PA5-97398
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphorylated peptide around S104 of human PEA15 (NP_0037591)
Conjugate
Form
Liquid
Concentration
0.53 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809200
Product Specific Information
Immunogen sequence: IPSAK; Positive Samples: HeLa, C6; Cellular Location: Cytoplasm
Target Information
PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 15 kDa phosphoprotein enriched in astrocytes; Astrocytic phosphoprotein PEA-15; homolog of mouse MAT-1 oncogene; mammary transforming gene 1; mammary transforming gene 1, mouse, homolog of; OTTHUMP00000029887; PED; phosphoprotein enriched in astrocytes 15; phosphoprotein enriched in astrocytes 15A; Phosphoprotein enriched in diabetes
Gene Aliases: HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PEA15; Pea15a; PED; Pkcs15
UniProt ID: (Human) Q15121, (Rat) Q5U318, (Mouse) Q62048
Entrez Gene ID: (Human) 8682, (Rat) 364052, (Mouse) 18611
DNA damage checkpoint
MAPK cascade
activation of MAPK activity
transport
apoptotic process
carbohydrate transport
response to morphine
negative regulation of glucose import
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
intracellular signal transduction
regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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