Invitrogen

Phospho-PKC zeta/lambda (Thr410, Thr403) Polyclonal Antibody

2 References

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-17837

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
View 2 publications 2 publications
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr410 of human PKC zeta
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10986758

Product Specific Information

It is not recommended to aliquot this antibody.



This antibody is not cross-reactive with endogenous levels of other PKC isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 14 - 3 - 3 - zeta isoform; atypical protein kinase C; nPKC-eta; nPKC-zeta; PKC-L; PRKCI; Protein kinase C eta type; protein kinase C zeta subspecies; Protein kinase C zeta type; protein kinase C, eta; protein kinase C, zeta; protein kinase C-eta

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Gene Aliases: 14-3-3-zetaisoform; AI098070; aPKCzeta; C80388; nPKC-eta; nPKC-zeta; PKC-L; PKC-ZETA; PKC2; Pkch; PKCL; Pkcz; PRKCH; PRKCL; PRKCZ; r14-3-3; R74924; zetaPKC

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UniProt ID: (Human) P24723, (Human) Q05513, (Mouse) P23298, (Rat) Q64617, (Rat) P09217, (Mouse) Q02956

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Entrez Gene ID: (Human) 5583, (Human) 5590, (Mouse) 18755, (Rat) 81749, (Rat) 25522, (Mouse) 18762

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Function(s)
protein kinase C activity calcium-independent protein kinase C activity ATP binding Ral GTPase binding enzyme binding metal ion binding protein kinase activity protein serine/threonine kinase activity protein binding potassium channel regulator activity protein kinase binding protein domain specific binding phospholipase binding insulin receptor substrate binding 14-3-3 protein binding nucleotide binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups
Process(es)
microtubule cytoskeleton organization positive regulation of cell-matrix adhesion protein phosphorylation inflammatory response signal transduction cell surface receptor signaling pathway long-term memory positive regulation of cell proliferation insulin receptor signaling pathway cell migration peptidyl-serine phosphorylation establishment of cell polarity negative regulation of protein complex assembly actin cytoskeleton reorganization activation of phospholipase D activity activation of protein kinase B activity positive regulation of interleukin-4 production cellular response to insulin stimulus cellular protein localization intracellular signal transduction negative regulation of apoptotic process positive regulation of T-helper 2 cell differentiation positive regulation of glucose import negative regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway vesicle transport along microtubule negative regulation of peptidyl-tyrosine phosphorylation positive regulation of synaptic transmission positive regulation of NF-kappaB transcription factor activity positive regulation of protein transport protein heterooligomerization negative regulation of hydrolase activity membrane depolarization membrane hyperpolarization long-term synaptic potentiation positive regulation of ERK1 and ERK2 cascade protein kinase C signaling protein localization to plasma membrane neuron projection extension positive regulation of excitatory postsynaptic potential positive regulation of T-helper 2 cell cytokine production positive regulation of interleukin-5 secretion positive regulation of interleukin-13 secretion positive regulation of interleukin-10 secretion positive regulation of macrophage derived foam cell differentiation phosphorylation cell differentiation negative regulation of glial cell apoptotic process positive regulation of keratinocyte differentiation positive regulation of B cell receptor signaling pathway positive regulation of glial cell proliferation regulation of bicellular tight junction assembly platelet activation transforming growth factor beta receptor signaling pathway
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