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Invitrogen
Phospho-PLCB3 (Ser537) Polyclonal Antibody
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Product Details
PA5-17833
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phosphopeptide corresponding residues surrounding pSer537 of human PLCbeta3
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10987252
Product Specific Information
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with phosphorylated PLCbeta1, PLCbeta2, PLCbeta4 or other PLCs.
Target Information
PLCB3 encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; phosphoinositide-specific phospholipase c; phospholipase C, beta 3 (phosphatidylinositol-specific); Phospholipase C-beta-3; PLC beta 3; PLC-beta-3; PLC-beta3; PLCbeta3
Gene Aliases: PLCB3
UniProt ID: (Human) Q01970
Entrez Gene ID: (Human) 5331
regulation of systemic arterial blood pressure
post-Golgi vesicle-mediated transport
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
chemical synaptic transmission
lipid catabolic process
intracellular signal transduction
inositol phosphate metabolic process
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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