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Phospho-RAD9 (Ser272) Antibody (PA5-105762) in WB
Western blot analysis of Phospho-RAD9 (Ser272) in extracts from Raji cells (serum starvation treatment). Samples were incubated with Phospho-RAD9 (Ser272) polyclonal antibody (Product # PA5-105762). The lane on the left was treated with blocking peptide.
Product Details
PA5-105762
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RAD9A(Accession Q99638), corresponding to amino acid residues around phosphorylated Ser272.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2817161
Product Specific Information
Antibody detects endogenous levels of RAD9 only when phosphorylated at Ser272.
Target Information
RAD9 is a component of the 9-1-1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesions upon damage by the RAD17-replication factor C clamp loader complex. RAD9 acts as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell cycle checkpoint control protein RAD9A; DNA repair exonuclease rad9 homolog A; hRAD9; RAD9 homolog A
Gene Aliases: RAD9; RAD9A
UniProt ID: (Human) Q99638
Entrez Gene ID: (Human) 5883
DNA replication checkpoint
DNA damage checkpoint
DNA replication
DNA repair
cellular response to DNA damage stimulus
intra-S DNA damage checkpoint
cellular response to ionizing radiation
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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