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Invitrogen
Phospho-SCRIB (Ser1220) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-SCRIB (Ser1220) Antibody (PA5-105210) in WB
Western blot analysis of Phospho-SCRIB (Ser1220) in HCT 116 (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-SCRIB (Ser1220) polyclonal antibody (Product # PA5-105210).
Product Details
PA5-105210
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SCRIB(Accession Q14160), corresponding to amino acid residues around phosphorylated Ser1220.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2816683
Product Specific Information
Antibody detects endogenous levels of Scribble only when phosphorylated at Ser1220.
Target Information
SCRIB is a cytoplasmic multimodular scaffold protein targeted to epithelial adherens junctions and neuronal presynaptic compartments. SCRIB and its orthologs in vertebrates and invertebrates participate in cell polarization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: circletail; hScrib; PDZ-domain protein scribble; Protein LAP4; Protein scribble homolog; S Vartul; Scribble; scribble homolog 1; scribbled homolog
Gene Aliases: AI118201; Crc; CRIB; CRIB1; KIAA0147; LAP4; mKIAA0147; SCRB1; SCRIB; SCRIB1; VARTUL
UniProt ID: (Human) Q14160, (Mouse) Q80U72
Entrez Gene ID: (Human) 23513, (Mouse) 105782
neural tube closure
positive regulation of receptor recycling
auditory receptor cell morphogenesis
multicellular organism development
asymmetric protein localization
cell proliferation
synaptic vesicle targeting
morphogenesis of embryonic epithelium
single organismal cell-cell adhesion
cell migration
cochlear nucleus development
cell differentiation
establishment of apical/basal cell polarity
wound healing
positive regulation of apoptotic process
astrocyte cell migration
negative regulation of mitotic cell cycle
synaptic vesicle endocytosis
positive chemotaxis
auditory receptor cell stereocilium organization
apoptotic process involved in morphogenesis
mammary gland duct morphogenesis
protein localization to adherens junction
activation of GTPase activity
viral process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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