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Bioss
Phospho-STX1A (Ser188) Polyclonal Antibody
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Phospho-STX1A (Ser188) Antibody (BS-10315R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse embryo; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-Syntaxin 1a(Ser188) Polyclonal Antibody, Unconjugated (bs-10315R) at 1:200 overnight at 4°C, followed by a conjugated secon... View More
Product Details
BS-10315R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Syntaxin-1A around the phosphorylation site of Ser188.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Plays a role in hormone and neurotransmitter exocytosis. Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Neuron-specific antigen HPC-1; P35A; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A (brain); syntaxin 1A (brain)-like; Syntaxin-1A
Gene Aliases: HPC-1; P35-1; Sap; STX1; STX1A; SYN1A
UniProt ID: (Human) Q16623, (Mouse) O35526, (Rat) P32851
Entrez Gene ID: (Human) 6804, (Mouse) 20907, (Rat) 116470
SNARE binding
glycoprotein binding
SNAP receptor activity
protein binding
myosin binding
calcium channel inhibitor activity
chloride channel inhibitor activity
kinase binding
protein domain specific binding
protein binding, bridging
myosin head/neck binding
ATP-dependent protein binding
ion channel binding
protein heterodimerization activity
protein N-terminus binding
calcium-dependent protein binding
positive regulation of neurotransmitter secretion
transport
neurotransmitter transport
intracellular protein transport
exocytosis
response to gravity
positive regulation of norepinephrine secretion
regulation of synaptic vesicle priming
vesicle-mediated transport
calcium ion regulated exocytosis
regulation of exocytosis
synaptic vesicle fusion to presynaptic active zone membrane
secretion by cell
positive regulation of catecholamine secretion
positive regulation of exocytosis
positive regulation of calcium ion-dependent exocytosis
vesicle docking
positive regulation of excitatory postsynaptic potential
neurotransmitter secretion
glutamate secretion
synaptic vesicle docking
regulation of insulin secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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