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Phospho-TIE1 (Tyr1117) Antibody (PA5-105921) in ICC/IF
Immunocytochemistry analysis of Phospho-TIE1 (Tyr1117) in Hela cells (Etoposide 25 μm for 5h). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-TIE1 (Tyr1117) polyclonal antibody (Product # PA5-105921) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabb... View More
Product Details
PA5-105921
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TIE1(Accession P35590), corresponding to amino acid residues around phosphorylated Tyr1117.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2817320
Product Specific Information
Antibody detects endogenous levels of TIE1 only when phosphorylated at Tyr1117.
Target Information
Probable protein tyrosine-kinase transmembrane receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: tyrosine kinase receptor 1; tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; Tyrosine-protein kinase receptor Tie-1
Gene Aliases: D430008P04Rik; JTK14; TIE; Tie-1; TIE1
UniProt ID: (Human) P35590, (Mouse) Q06806
Entrez Gene ID: (Human) 7075, (Mouse) 21846, (Rat) 89806
angiogenesis
vasculogenesis
in utero embryonic development
signal transduction
mesoderm development
negative regulation of angiogenesis
peptidyl-tyrosine phosphorylation
negative regulation of cell migration
response to retinoic acid
plasma membrane fusion
blood vessel development
protein phosphorylation
phosphorylation
Performance Guarantee
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