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Invitrogen
Phospho-USF1 (Thr153) Polyclonal Antibody
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FIGURE: 1 / 5
Phospho-USF1 (Thr153) Antibody (PA5-99572) in IHC (P)
Immunohistochemistry analysis of Phospho-USF1 (Thr153) in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-USF1 (Thr153) polyclonal antibody (Product # PA5-99572) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-99572
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human USF1(Accession P22415), corresponding to amino acid residues around phosphorylated Thr153.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818505
Product Specific Information
Antibody detects endogenous levels of USF1 only when phosphorylated at Thr153.
Target Information
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHb11; Class B basic helix-loop-helix protein 11; Major late transcription factor 1; Upstream stimulatory factor 1; usf1-bd
Gene Aliases: BHLHB11; FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; USF; USF1
UniProt ID: (Human) P22415, (Mouse) Q61069
Entrez Gene ID: (Human) 7391, (Rat) 83586, (Mouse) 22278
double-stranded DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
enzyme binding
protein kinase binding
protein homodimerization activity
histone deacetylase binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
DNA binding
transcription factor activity, sequence-specific DNA binding
regulation of transcription from RNA polymerase II promoter by glucose
positive regulation of transcription from RNA polymerase II promoter by glucose
response to hypoxia
glucose metabolic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to UV
late viral transcription
cellular response to insulin stimulus
glucose homeostasis
positive regulation of transcription from RNA polymerase II promoter
carbon catabolite regulation of transcription
negative regulation of fibrinolysis
lipid homeostasis
regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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