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This antibody detects a 60- kDa band, which has been reported and likely represents a fragment resulting from cleavage of Pikachurin.
Immunogen sequence: MRFKTTAKD GLLLWRGDSP MRPNSDFISL GLRDGALVFS YNLGSGVASI MVNGSFNDGR WHRVKAVRDG QSGKITVDDY GARTGKSPGM MRQLNINGAL YVGGMKEIAL HTNRQYMRGL VGCISHFTLS TDYHISLVED SVDGKNINTC GAK (1-152 aa encoded by BC033177)
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Agrin-like protein; EGF-like, fibronectin type III and laminin G domains; EGF-like, fibronectin type-III and laminin G-like domain-containing protein; Nectican; Pikachurin
Gene Aliases: 5930412K08; AGRINL; AGRNL; AU040377; EGFLAM; PIKA; RGD1306592
UniProt ID: (Human) Q63HQ2, (Rat) B4F785, (Mouse) Q4VBE4
Entrez Gene ID: (Human) 133584, (Rat) 365691, (Mouse) 268780
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