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Product Details
PA5-30963
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Pirh2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.88 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548437
Product Specific Information
Recommended positive controls: NT2D1.
Predicted reactivity: Human (99%), Mouse (93%), Rat (94%), Xenopus laevis (83%), Pig (96%), Chicken (86%), Sheep (90%), Rhesus Monkey (99%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Androgen receptor N-terminal-interacting protein; androgen-receptor N-terminal-interacting protein; CH-rich interacting match with PLAG1; CH-rich-interacting match with PLAG1; DKFZp586C1620; E3 ubiquitin-protein ligase Pirh2; h PRO1996; hPirh2; p53-induced protein with a RING-H2 domain; p53-induced RING-H2 protein; PIRH2E; PIRH2F; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; Zinc finger protein 363; zinc finger, CHY-type
Gene Aliases: ARNIP; CHIMP; PIRH2; PRO1996; RCHY1; RNF199; ZCHY; ZNF363
UniProt ID: (Human) Q96PM5
Entrez Gene ID: (Human) 25898
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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