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Recommended positive controls: HeLa, mouse liver.
Predicted reactivity: Mouse (95%), Rat (96%), Rhesus Monkey (98%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: iron-binding nuclear protein; Pirin; pirin (iron-binding nuclear protein); pirin like; pirinin; Probable quercetin 2,3-dioxygenase PIR; Probable quercetinase
Gene Aliases: 2310042L19Rik; PIR; Pirnl
UniProt ID: (Human) O00625, (Rat) Q5M827, (Mouse) Q9D711
Entrez Gene ID: (Human) 8544, (Rat) 363465, (Mouse) 69656
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