Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Progen
Plakoglobin Monoclonal Antibody (PG 5.1)
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
690005S
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
PG 5.1
Immunogen
Plakoglobin, "band 5" protein from bovine snout epidermis
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Target Information
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gama-catenin; Gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; Junction plakoglobin a; OTTHUMP00000164735; Plakoglobin; Plakoglobin-1a
Gene Aliases: ARVD12; BOS_19078; cb80; CTNNG; D930025P04Rik; danPG; DP3; DPIII; fb11b06; JUP; jupa; PDGB; PG; PKGB; wu:fb11b06
UniProt ID: (Bovine) Q8SPJ1, (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257, (Zebrafish) Q9PVF7
Entrez Gene ID: (Bovine) 445543, (Dog) 480522, (Human) 3728, (Rat) 81679, (Mouse) 16480, (Zebrafish) 30415
transcription coactivator activity
structural molecule activity
protein binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity
alpha-catenin binding
cadherin binding
signal transducer activity
structural constituent of cell wall
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
cadherin binding involved in cell-cell adhesion
nuclear hormone receptor binding
negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
desmosome assembly
negative regulation of heart induction by canonical Wnt signaling pathway
atrioventricular valve morphogenesis
negative regulation of Wnt signaling pathway involved in heart development
cytoskeletal anchoring at plasma membrane
gastrulation
ectoderm development
nervous system development
morphogenesis of embryonic epithelium
cell migration
regulation of cell proliferation
positive regulation of protein import into nucleus
regulation of apoptotic process
skin development
oocyte development
detection of mechanical stimulus
positive regulation of sequence-specific DNA binding transcription factor activity
endothelial cell-cell adhesion
cellular response to indole-3-methanol
ventricular cardiac muscle cell action potential
bundle of His cell to Purkinje myocyte communication
regulation of heart rate by cardiac conduction
cell adhesion
heart development
negative regulation of Wnt signaling pathway
positive regulation of transcription from RNA polymerase II promoter
signal transduction
single organismal cell-cell adhesion
adherens junction organization
adherens junction assembly
protein heterooligomerization
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
establishment of protein localization to plasma membrane
positive regulation of canonical Wnt signaling pathway
regulation of ventricular cardiac muscle cell action potential
regulation of cell fate specification
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support