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Proteintech
Plakophilin 3 Polyclonal Antibody
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Product Details
18338-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Plakophilin 3 Fusion Protein Ag13062 (170-400 aa encoded by BC000081)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VGSRADYDT LSLRSLRLGP GGLDDRYSLV SEQLEPAATS TYRAFAYERQ ASSSSSRAGG LDWPEATEVS PSRTIRAPAV RTLQRFQSSH RSRGVGGAVP GAVLEPVARA PSVRSLSLSL ADSGHLPDVH GFNSYGSHRT LQRLSSGFDD IDLPSAVKYL MASDPNLQVL GAAYIQHKCY SDAAAKKQAR SLQAVPRLVK LFNHANQEVQ RHATGAMRNL IYDNADNKLA LV (170-400 aa encoded by BC000081)
Target Information
Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: plakophilin 3b; Plakophilin-3
Gene Aliases: 2310056L12Rik; PKP3
UniProt ID: (Human) Q9Y446, (Mouse) Q9QY23
Entrez Gene ID: (Human) 11187, (Mouse) 56460, (Rat) 293619
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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