Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
NeoBiotechnologies
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Monoclonal Antibody (2A4)
Product Details
5420-MSM3-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgM, kappa
Class
Monoclonal
Type
Antibody
Clone
2A4
Immunogen
A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GCTM-2 antigen; Gp200; MGC138240; PC; PCLP antibody; PCLP1 antibody; PODLX2; Podocalyxin; podocalyxin-like; Podocalyxin-like protein 1; podolyxin
Gene Aliases: Gp200; PC; PCLP; PCLP-1; PCLP1; podocalyxin; PODXL
UniProt ID: (Rabbit) Q28645, (Human) O00592, (Rat) Q9WTQ2
Entrez Gene ID: (Rabbit) 100009552, (Human) 5420, (Rat) 192181
cell adhesion
negative regulation of cell adhesion
cell migration
negative regulation of cell-cell adhesion
positive regulation of cell migration
regulation of microvillus assembly
positive regulation of cell-cell adhesion mediated by integrin
leukocyte migration
glomerular visceral epithelial cell development
epithelial tube formation
glomerular filtration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support