Product References
Pbp1 associates with Puf3 and promotes translation of its target mRNAs involved in mitochondrial biogenesis.
PLoS genetics
van de Poll F,Sutter BM,Acoba MG,Caballero D,Jahangiri S,Yang YS,Lee CD,Tu BP
459500 was used in Western Blot to reveal a key role for Pbp1-containing assemblies in enabling the translation of mRNAs critical for mitochondrial biogenesis and respiration.
Mon May 01 00:00:00 UTC 2023
Pbp1 associates with Puf3 and promotes translation of its target mRNAs involved in mitochondrial biogenesis.
PLoS genetics
van de Poll F,Sutter BM,Acoba MG,Caballero D,Jahangiri S,Yang YS,Lee CD,Tu BP
459500 was used in Western Blot to reveal a key role for Pbp1-containing assemblies in enabling the translation of mRNAs critical for mitochondrial biogenesis and respiration.
Mon May 01 00:00:00 UTC 2023
The ERAD system is restricted by elevated ceramides.
Science advances
Hwang J,Peterson BG,Knupp J,Baldridge RD
459500 was used in Western Blot to reveal a previously unrecognized mechanism in which ER membrane lipid remodeling changes the activity of ERAD.
Fri Jan 13 00:00:00 UTC 2023
Molecular determinants of inhibition of UCP1-mediated respiratory uncoupling.
Nature communications
Gagelin A,Largeau C,Masscheleyn S,Piel MS,Calderón-Mora D,Bouillaud F,Hénin J,Miroux B
459500 was used in Western Blot to provide a molecular understanding of the selective inhibition of UCP1 by purine nucleotides.
Fri May 05 00:00:00 UTC 2023
Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome.
The Journal of cell biology
Rogers S,Gui L,Kovalenko A,Zoni V,Carpentier M,Ramji K,Ben Mbarek K,Bacle A,Fuchs P,Campomanes P,Reetz E,Speer NO,Reynolds E,Thiam AR,Vanni S,Nicastro D,Henne WM
459500 was used in Western Blotting to suggest glucose restriction drives TG mobilization, which alters the phase properties of LD lipids and selectively remodels the LD proteome.
Mon Nov 07 00:00:00 UTC 2022
Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome.
The Journal of cell biology
Rogers S,Gui L,Kovalenko A,Zoni V,Carpentier M,Ramji K,Ben Mbarek K,Bacle A,Fuchs P,Campomanes P,Reetz E,Speer NO,Reynolds E,Thiam AR,Vanni S,Nicastro D,Henne WM
459500 was used in Western Blotting to suggest glucose restriction drives TG mobilization, which alters the phase properties of LD lipids and selectively remodels the LD proteome.
Mon Nov 07 00:00:00 UTC 2022
Loss of Num1-mediated cortical dynein anchoring negatively impacts respiratory growth.
Journal of cell science
White AJ,Harper CS,Rosario EM,Dietz JV,Addis HG,Fox JL,Khalimonchuk O,Lackner LL
459500 was used in Western Blotting to elucidate the impacts of Num1 on mitochondrial function.
Tue Nov 01 00:00:00 UTC 2022
Coordination of metal center biogenesis in human cytochrome c oxidase.
Nature communications
Nývltová E,Dietz JV,Seravalli J,Khalimonchuk O,Barrientos A
459500 was used in Western Blotting to report that in human cells the CcO copper chaperones form macromolecular assemblies and cooperate with several twin CX9C proteins to control heme a biosynthesis and coordinate copper transfer sequentially to the CuA and CuB sites.
Fri Jun 24 00:00:00 UTC 2022
TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis.
Cell death & disease
Lalier L,Mignard V,Joalland MP,Lanoé D,Cartron PF,Manon S,Vallette FM
459500 was used in Western Blotting to investigate the mechanisms that link the ER-mitochondria contacts, called mitochondria-associated membranes, and apoptosis by examining the subcellular localization of Bcl2 family members.
Mon Feb 15 00:00:00 UTC 2021
TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis.
Cell death & disease
Lalier L,Mignard V,Joalland MP,Lanoé D,Cartron PF,Manon S,Vallette FM
459500 was used in Western Blotting to investigate the mechanisms that link the ER-mitochondria contacts, called mitochondria-associated membranes, and apoptosis by examining the subcellular localization of Bcl2 family members.
Mon Feb 15 00:00:00 UTC 2021
Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase.
Redox biology
Dietz JV,Willoughby MM,Piel RB,Ross TA,Bohovych I,Addis HG,Fox JL,Lanzilotta WN,Dailey HA,Wohlschlegel JA,Reddi AR,Medlock AE,Khalimonchuk O
459500 was used in Western Blotting to investigate the molecular organization as well as the physical and genetic interactions of the terminal heme synthesis pathway enzyme, ferrochelatase (Hem15), in the yeast Saccharomyces cerevisiae.
Fri Oct 01 00:00:00 UTC 2021
Mitochondrial-nuclear heme trafficking in budding yeast is regulated by GTPases that control mitochondrial dynamics and ER contact sites.
Journal of cell science
Martinez-Guzman O,Willoughby MM,Saini A,Dietz JV,Bohovych I,Medlock AE,Khalimonchuk O,Reddi AR
459500 was used in Western Blotting to indicate that there are parallel pathways for the distribution of bioavailable heme.
Wed May 20 00:00:00 UTC 2020
Overexpression of Mdm36 reveals Num1 foci that mediate dynein-dependent microtubule sliding in budding yeast.
Journal of cell science
Omer S,Brock K,Beckford J,Lee WL
459500 was used in Western Blot to show that cortical clustering of Num1, the yeast dynein attachment molecule, is limited by its assembly factor Mdm36.
Thu Oct 15 00:00:00 UTC 2020
Human apolipoprotein L1 interferes with mitochondrial function in Saccharomyces cerevisiae.
Molecular medicine reports
Chidiac M,Daher J,Boeckstaens M,Poelvoorde P,Badran B,Marini AM,Khalaf R,Vanhamme L
459500 was used in Western Blotting to present evidence which suggests that APOL1 could be a physiological regulator of mitochondrial function.
Tue Sep 01 00:00:00 UTC 2020
Pex14p Phosphorylation Modulates Import of Citrate Synthase 2 Into Peroxisomes in Saccharomyces cerevisiae.
Frontiers in cell and developmental biology
Schummer A,Maier R,Gabay-Maskit S,Hansen T,Mühlhäuser WWD,Suppanz I,Fadel A,Schuldiner M,Girzalsky W,Oeljeklaus S,Zalckvar E,Erdmann R,Warscheid B
459500 was used in Western Blotting to indicate that phosphorylation of Pex14p at S266 provides a mechanism for controlling the peroxisomal import of Cit2p, which helps S. cerevisiae cells to adjust their carbohydrate metabolism according to the nutritional conditions.
Tue Oct 13 00:00:00 UTC 2020
Mitochondrial AAA-ATPase Msp1 detects mislocalized tail-anchored proteins through a dual-recognition mechanism.
EMBO reports
Li L,Zheng J,Wu X,Jiang H
459500 was used in Western Blotting to suggest that mislocalized TA proteins expose hydrophobic surfaces in the cytoplasm and are recognized by Msp1 through conserved hydrophobic residues.
Mon Apr 01 00:00:00 UTC 2019
Redox Regulation of the Mitochondrial Quality Control Protease Oma1.
Antioxidants & redox signaling
Bohovych I,Dietz JV,Swenson S,Zahayko N,Khalimonchuk O
459500 was used in Western Blot to propose that the redox status of these cysteines may act as a redox-tunable switch to optimize Oma1 proteolytic function for specific cellular conditions or homeostatic challenges.
Tue Aug 20 00:00:00 UTC 2019
The mitochondrial phosphatidylserine decarboxylase Psd1 is involved in nitrogen starvation-induced mitophagy in yeast.
Journal of cell science
Vigié P,Cougouilles E,Bhatia-Kiššová I,Salin B,Blancard C,Camougrand N
459500 was used in Western Blotting to suggest that the mitophagy defect observed in δpsd1 yeast cells after nitrogen starvation may be due to a failure of Atg8 recruitment to mitochondria.
Wed Jan 02 00:00:00 UTC 2019
Extra-mitochondrial Cu/Zn superoxide dismutase (Sod1) is dispensable for protection against oxidative stress but mediates peroxide signaling in Saccharomyces cerevisiae.
Redox biology
Montllor-Albalate C,Colin AE,Chandrasekharan B,Bolaji N,Andersen JL,Wayne Outten F,Reddi AR
459500 was used in Western Blotting to show that the vast majority of Sod1 in yeast is utilised for peroxide-mediated signalling rather than superoxide scavenging.
Fri Feb 01 00:00:00 UTC 2019
Protein AMPylation by an Evolutionarily Conserved Pseudokinase.
Cell
Sreelatha A,Yee SS,Lopez VA,Park BC,Kinch LN,Pilch S,Servage KA,Zhang J,Jiou J,Karasiewicz-Urbańska M,Łobocka M,Grishin NV,Orth K,Kucharczyk R,Pawłowski K,Tomchick DR,Tagliabracci VS
Published figure using Porin monoclonal antibody (Product # 459500) in Western Blot
Thu Oct 18 00:00:00 UTC 2018
Mitochondrial inner-membrane protease Yme1 degrades outer-membrane proteins Tom22 and Om45.
The Journal of cell biology
Wu X,Li L,Jiang H
Published figure using Porin monoclonal antibody (Product # 459500) in Western Blot
Tue Jan 02 00:00:00 UTC 2018
Cox15 interacts with the cytochrome bc1 dimer within respiratory supercomplexes as well as in the absence of cytochrome c oxidase.
The Journal of biological chemistry
Herwaldt EJ,Rivett ED,White AJ,Hegg EL
459500 was used in Western Blotting to investigate the protein-protein interactions that involve Cox15 in S. cerevisiae.
Fri Oct 19 00:00:00 UTC 2018
Biochemical, Molecular, and Clinical Characterization of Succinate Dehydrogenase Subunit A Variants of Unknown Significance.
Clinical cancer research : an official journal of the American Association for Cancer Research
Bannon AE,Kent J,Forquer I,Town A,Klug LR,McCann K,Beadling C,Harismendy O,Sicklick JK,Corless C,Shinde U,Heinrich MC
459500 was used in Western Blotting to determine the pathogenicity of different Succinate Dehydrogenase (SDH) Subunit variants of unknown significance, and highlight the need for thorough functional assessment of inherited SDH variants.
Wed Nov 01 00:00:00 UTC 2017
The Assembly Factor Pet117 Couples Heme a Synthase Activity to Cytochrome Oxidase Assembly.
The Journal of biological chemistry
Taylor NG,Swenson S,Harris NJ,Germany EM,Fox JL,Khalimonchuk O
459500 was used in western blot to propose that Pet117 mediates coupling of heme a synthesis to the cytochrome c oxidase assembly process
Fri Feb 03 00:00:00 UTC 2017
The Assembly Factor Pet117 Couples Heme a Synthase Activity to Cytochrome Oxidase Assembly.
The Journal of biological chemistry
Taylor NG,Swenson S,Harris NJ,Germany EM,Fox JL,Khalimonchuk O
459500 was used in western blot to propose that Pet117 mediates coupling of heme a synthesis to the cytochrome c oxidase assembly process
Fri Feb 03 00:00:00 UTC 2017
MoDnm1 Dynamin Mediating Peroxisomal and Mitochondrial Fission in Complex with MoFis1 and MoMdv1 Is Important for Development of Functional Appressorium in Magnaporthe oryzae.
PLoS pathogens
Zhong K,Li X,Le X,Kong X,Zhang H,Zheng X,Wang P,Zhang Z
459500 was used in western blot elucidate how MoDnm1 and its partner proteins regulate peroxisomal and mitochondrial functions
Mon Aug 01 00:00:00 UTC 2016
Proteasome Impairment Induces Recovery of Mitochondrial Membrane Potential and an Alternative Pathway of Mitochondrial Fusion.
Molecular and cellular biology
Shirozu R,Yashiroda H,Murata S
459500 was used in western blot to investigate the role of the proteasome in the regulation of mitochondrial quality
Fri Jan 15 00:00:00 UTC 2016
Proteasome Impairment Induces Recovery of Mitochondrial Membrane Potential and an Alternative Pathway of Mitochondrial Fusion.
Molecular and cellular biology
Shirozu R,Yashiroda H,Murata S
459500 was used in western blot to investigate the role of the proteasome in the regulation of mitochondrial quality
Fri Jan 15 00:00:00 UTC 2016
Heterologous expression of the Crassostrea gigas (Pacific oyster) alternative oxidase in the yeast Saccharomyces cerevisiae.
Journal of bioenergetics and biomembranes
Robertson A,Schaltz K,Neimanis K,Staples JF,McDonald AE
459500 was used in western blot to express AOX from Crassostrea gigas in Saccharomyces cerevisiae and study its function
Sat Oct 01 00:00:00 UTC 2016
Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes.
The Journal of biological chemistry
Swenson S,Cannon A,Harris NJ,Taylor NG,Fox JL,Khalimonchuk O
459500 was used in western blot to study Heme a synthase oligomerization properties to gain insights into its function in eukaryotes
Fri May 06 00:00:00 UTC 2016
Twilight, a Novel Circadian-Regulated Gene, Integrates Phototropism with Nutrient and Redox Homeostasis during Fungal Development.
PLoS pathogens
Deng YZ,Qu Z,Naqvi NI
459500 was used in Western Blotting to examine a novel circadian-regulated Twilight function essential for phototropic induction of asexual development and pathogenesis in Magnaporthe oryzae.
Mon Jun 01 00:00:00 UTC 2015
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability.
Scientific reports
Bohovych I,Fernandez MR,Rahn JJ,Stackley KD,Bestman JE,Anandhan A,Franco R,Claypool SM,Lewis RE,Chan SS,Khalimonchuk O
459500 was used in western blot to study metalloprotease OMA1 and how it fine-tunes mitochondrial bioenergetic function and respiratory supercomplex stability
Mon Sep 14 00:00:00 UTC 2015
The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation.
The Journal of biological chemistry
Santarriaga S,Petersen A,Ndukwe K,Brandt A,Gerges N,Bruns Scaglione J,Scaglione KM
459500 was used in western blot to identify Dictyostelium as an organism that suppress aggregation of proteins with long polyglutamine tracts
Fri Oct 16 00:00:00 UTC 2015
Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan.
Mechanisms of ageing and development
Schroeder EA,Shadel GS
459500 was used in western blot to test the requirement for mtDNA in the adaptive mtROS longevity signal.
Wed Jan 01 00:00:00 UTC 2014
Investigating interference with apoptosis induction by bacterial proteins.
Methods in molecular biology (Clifton, N.J.)
Niu H,Rikihisa Y
459500 was used in immunocytochemistry to describe a method to study the anti-apoptotic effect of Ats-1.
Fri May 15 00:00:00 UTC 2015
Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols.
Nature biotechnology
Avalos JL,Fink GR,Stephanopoulos G
459500 was used in western blot to show that targeting metabolic pathways to mitochondria can increase production of compounds in yeast
Mon Apr 01 00:00:00 UTC 2013
Atg24-assisted mitophagy in the foot cells is necessary for proper asexual differentiation in Magnaporthe oryzae.
Autophagy
He Y,Deng YZ,Naqvi NI
459500 was used in Western Blotting to examine the role of mitophagy in the proper asexual differentiation of Magnaporthe oryzae.
Fri Nov 01 00:00:00 UTC 2013
Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis.
Aging
Richard VR,Leonov A,Beach A,Burstein MT,Koupaki O,Gomez-Perez A,Levy S,Pluska L,Mattie S,Rafesh R,Iouk T,Sheibani S,Greenwood M,Vali H,Titorenko VI
459500 was used in western blot to determine the physiological role of macromitophagy in yeast
Mon Apr 01 00:00:00 UTC 2013
Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis.
Aging
Richard VR,Leonov A,Beach A,Burstein MT,Koupaki O,Gomez-Perez A,Levy S,Pluska L,Mattie S,Rafesh R,Iouk T,Sheibani S,Greenwood M,Vali H,Titorenko VI
459500 was used in western blot to determine the physiological role of macromitophagy in yeast
Mon Apr 01 00:00:00 UTC 2013
The role of snx41-based pexophagy in magnaporthe development.
PloS one
Deng Y,Qu Z,Naqvi NI
459500 was used in western blot to study the role of pexophagy in the fungal pathogenic life cycle.
Wed Oct 01 00:00:00 UTC 2014
The role of snx41-based pexophagy in magnaporthe development.
PloS one
Deng Y,Qu Z,Naqvi NI
459500 was used in western blot to study the role of pexophagy in the fungal pathogenic life cycle.
Wed Oct 01 00:00:00 UTC 2014
Mitochondrial membrane lipidome defines yeast longevity.
Aging
Beach A,Richard VR,Leonov A,Burstein MT,Bourque SD,Koupaki O,Juneau M,Feldman R,Iouk T,Titorenko VI
459500 was used in western blot to assess how yeast longevity is defined by mitochondrial membrane lipidome
Mon Jul 01 00:00:00 UTC 2013
Repression of mitochondrial translation, respiration and a metabolic cycle-regulated gene, SLF1, by the yeast Pumilio-family protein Puf3p.
PloS one
Chatenay-Lapointe M,Shadel GS
459500 was used in western blot to study the coordination of gene expression between the nuclear and mitochondrial genomes.
Wed Oct 05 00:00:00 UTC 2011
Genetic and biochemical analysis of high iron toxicity in yeast: iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditions.
The Journal of biological chemistry
Lin H,Li L,Jia X,Ward DM,Kaplan J
459500 was used in western blot to identify suppressors of high iron toxicity in Deltaccc1 yeast cells
Fri Feb 04 00:00:00 UTC 2011
