Proteintech

Prealbumin/transthyretin Polyclonal Antibody

Prealbumin/transthyretin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Prealbumin/transthyretin Antibody (11891-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver cancer using 11891-1-AP (Prealbumin/transthyretin antibody) at dilution of 1:100 (under 40x lens).

Prealbumin/transthyretin Antibody in Western Blot (WB)

Product Image Gallery

Product Details

11891-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Prealbumin/transthyretin Fusion Protein Ag2499 (1-147 aa encoded by BC020791)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MASHRLLLL CLAGLVFVSE AGPTGTGESK CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT TEEEFVEGIY KVEIDTKSYW KALGISPFHE HAEVVFTAND SGPRRYTIAA LLSPYSYSTT AVVTNPKE (1-147 aa encoded by BC020791)

Target Information

Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Effect of Total Sphingomyelin Synthase Activity on Low Density Lipoprotein Catabolism in Mice.

bioRxiv : the preprint server for biology

Li Z,He M,Chen G,Worgall TS,Jiang XC

Tue Feb 07 00:00:00 UTC 2023

Ex utero monkey embryogenesis from blastocyst to early organogenesis.

Cell

Gong Y,Bai B,Sun N,Ci B,Shao H,Zhang T,Yao H,Zhang Y,Niu Y,Liu L,Zhao H,Wu H,Zhang L,Wang T,Li S,Wei Y,Yu Y,Ribeiro Orsi AE,Liu B,Ji W,Wu J,Chen Y,Tan T

Thu May 11 00:00:00 UTC 2023

A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Liu J,Song C,Nie C,Sun Y,Wang Y,Xue L,Fan M,Qian H,Wang L,Li Y

Sat Jan 01 00:00:00 UTC 2022

Neurovascular unit pathology is observed very early in disease progression in the mutant SOD1^G93A mouse model of amyotrophic lateral sclerosis.

Experimental neurology

Yoshikawa M,Aizawa S,Oppenheim RW,Milligan C

Fri Jul 01 00:00:00 UTC 2022

TTR exon-humanized mouse optimal for verifying new therapies for FAP.

Biochemical and biophysical research communications

Li Z,Kanazashi H,Tokashiki Y,Fujikawa R,Okagaki A,Katoh S,Kojima K,Haruna K,Matsushita N,Ishikawa TO,Chen H,Yamamura K

Sat Apr 09 00:00:00 UTC 2022

Single-Cell Transcriptomic Analysis of the Mouse Pancreas: Characteristic Features of Pancreatic Ductal Cells in Chronic Pancreatitis.

Genes

Mao X,Mao S,Wang L,Jiang H,Deng S,Wang Y,Ye J,Li Z,Zou W,Liao Z

Sun Jun 05 00:00:00 UTC 2022

Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.

Theranostics

Liu J,Nie C,Xue L,Yan Y,Liu S,Sun J,Fan M,Qian H,Ying H,Wang L,Li Y

Wed Jan 19 00:00:00 UTC 2022

Plasma Exosome Profile in ST-Elevation Myocardial Infarction Patients with and without Out-of-Hospital Cardiac Arrest.

International journal of molecular sciences

Zarà M,Campodonico J,Cosentino N,Biondi ML,Amadio P,Milanesi G,Assanelli E,Cerri S,Biggiogera M,Sandrini L,Tedesco CC,Veglia F,Trabattoni D,Blandini F,Tremoli E,Marenzi G,Barbieri SS

Wed Jul 28 00:00:00 UTC 2021

Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice.

Toxicology reports

Shimada A,Hasegawa-Ishii S

Tue Mar 23 00:00:00 UTC 2021

Different Serotypes of Adeno-Associated Virus Vector- and Lentivirus-Mediated Tropism in Choroid Plexus by Intracerebroventricular Delivery.

Human gene therapy

Chen X,He Y,Tian Y,Wang Y,Wu Z,Lan T,Wang H,Cheng K,Xie P

Wed Apr 01 00:00:00 UTC 2020

RNA-seq analysis of palatal transcriptome changes in all-trans retinoic acid-induced cleft palate of mice.

Environmental toxicology and pharmacology

Peng Y,Wang XH,Su CN,Qiao WW,Gao Q,Sun XF,Meng LY

Sun Nov 01 00:00:00 UTC 2020

Destabilised human transthyretin shapes the morphology of calcium carbonate crystals.

Biochimica et biophysica acta. General subjects

Wieczorek E,Chitruń A,Ożyhar A

Fri Feb 01 00:00:00 UTC 2019

Destabilised human transthyretin shapes the morphology of calcium carbonate crystals.

Biochimica et biophysica acta. General subjects

Wieczorek E,Chitruń A,Ożyhar A

Fri Feb 01 00:00:00 UTC 2019

Is Transthyretin a Regulator of Ubc9 SUMOylation?

PloS one

Wieczorek E,Kędracka-Krok S,Sołtys K,Jankowska U,Hołubowicz R,Seliga J,Ożyhar A

Wed Aug 02 00:00:00 UTC 2017

Is Transthyretin a Regulator of Ubc9 SUMOylation?

PloS one

Wieczorek E,Kędracka-Krok S,Sołtys K,Jankowska U,Hołubowicz R,Seliga J,Ożyhar A

Wed Aug 02 00:00:00 UTC 2017

Up-Regulation of Antioxidant Proteins in the Plasma Proteome during Saturation Diving: Unique Coincidence under Hypobaric Hypoxia.

PloS one

Domoto H,Iwaya K,Ikomi F,Matsuo H,Tadano Y,Fujii S,Tachi K,Itoh Y,Sato M,Inoue K,Shinomiya N

Tue Jun 13 00:00:00 UTC 2017

Up-Regulation of Antioxidant Proteins in the Plasma Proteome during Saturation Diving: Unique Coincidence under Hypobaric Hypoxia.

PloS one

Domoto H,Iwaya K,Ikomi F,Matsuo H,Tadano Y,Fujii S,Tachi K,Itoh Y,Sato M,Inoue K,Shinomiya N

Tue Jun 13 00:00:00 UTC 2017

Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.

Diabetes

Zemany L,Bhanot S,Peroni OD,Murray SF,Moraes-Vieira PM,Castoldi A,Manchem P,Guo S,Monia BP,Kahn BB

Fri May 01 00:00:00 UTC 2015

Distinct neural stem cell tropism, early immune activation, and choroid plexus pathology following coxsackievirus infection in the neonatal central nervous system.

Laboratory investigation; a journal of technical methods and pathology

Puccini JM,Ruller CM,Robinson SM,Knopp KA,Buchmeier MJ,Doran KS,Feuer R

Sat Feb 01 00:00:00 UTC 2014

Distinct neural stem cell tropism, early immune activation, and choroid plexus pathology following coxsackievirus infection in the neonatal central nervous system.

Laboratory investigation; a journal of technical methods and pathology

Puccini JM,Ruller CM,Robinson SM,Knopp KA,Buchmeier MJ,Doran KS,Feuer R

Sat Feb 01 00:00:00 UTC 2014

Spatially dependent dynamic MAPK modulation by the Nde1-Lis1-Brap complex patterns mammalian CNS.

Developmental cell

Lanctot AA,Peng CY,Pawlisz AS,Joksimovic M,Feng Y

Mon May 13 00:00:00 UTC 2013

Spatially dependent dynamic MAPK modulation by the Nde1-Lis1-Brap complex patterns mammalian CNS.

Developmental cell

Lanctot AA,Peng CY,Pawlisz AS,Joksimovic M,Feng Y

Mon May 13 00:00:00 UTC 2013

Proteome analysis of human cerebrospinal fluid as a diagnostic biomarker in patients with meningioma.

Medical science monitor : international medical journal of experimental and clinical research

Kim JH,Lee SK,Yoo YC,Park NH,Park DB,Yoo JS,An HJ,Park YM,Cho KG

Thu Nov 01 00:00:00 UTC 2012

Proteome analysis of human cerebrospinal fluid as a diagnostic biomarker in patients with meningioma.

Medical science monitor : international medical journal of experimental and clinical research

Kim JH,Lee SK,Yoo YC,Park NH,Park DB,Yoo JS,An HJ,Park YM,Cho KG

Thu Nov 01 00:00:00 UTC 2012

A pediatric intramedullary spinal cord tumor with unusual solid-cystic and papillary features: a case report.

Neuropathology : official journal of the Japanese Society of Neuropathology

Iwasaki T,Kato M,Horie Y,Kato S,Akatsuka K,Watanabe T,Kuwamoto S,Murakami I,Hayashi K

Thu Dec 01 00:00:00 UTC 2011

A pediatric intramedullary spinal cord tumor with unusual solid-cystic and papillary features: a case report.

Neuropathology : official journal of the Japanese Society of Neuropathology

Iwasaki T,Kato M,Horie Y,Kato S,Akatsuka K,Watanabe T,Kuwamoto S,Murakami I,Hayashi K

Thu Dec 01 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: Amyloidosis I; ATTR; carpal tunnel syndrome 1; epididymis luminal protein 111; pre-albumin; Prealbumin; prealbumin, amyloidosis type I; TBPA; thyroxine-binding prealbumin; Transthyretin

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Gene Aliases: CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTR

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UniProt ID: (Human) P02766

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Entrez Gene ID: (Human) 7276

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Function(s)

hormone activity protein binding identical protein binding protein heterodimerization activity thyroid hormone binding

Process(es)

retinoid metabolic process purine nucleobase metabolic process transport extracellular matrix organization retinol metabolic process cellular protein metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Prealbumin/transthyretin Polyclonal Antibody

Prealbumin/transthyretin Antibody (11891-1-AP) in IHC (P)

Product Details

11891-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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