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Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activin AB beta polypeptide; Activin beta-B chain; activin betaB; Inhibin beta B chain; inhibin beta subunit B; inhibin, beta B; Inhibin, beta-2
Gene Aliases: INHBB
UniProt ID: (Human) P09529, (Mouse) Q04999, (Rat) P17491
Entrez Gene ID: (Human) 3625, (Mouse) 16324, (Rat) 25196
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