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Proteintech
ProSAPiP1 Polyclonal Antibody
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Product Details
24936-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ProSAPiP1 Fusion Protein Ag20765 (328-627 aa encoded by BC038860)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LWEKEQEVA ALRRSLEQSE AAVAQQDKKQ LQEEAARLMR QREELEDKVA ACQKEQADFL PRIEETKWEV CQKAGEISLL KQQLKDSQAD VSQKLSEIVG LRSQLREGRA SLREKEEQLL SLRDSFSSKQ ASLELGEGEL PAACLKPALT PVDPAEPQDA LATCESDEAK MRRQAGVAAA ASLVYVDGEA EAGGESGTRA LRREVGRLQA ELAAERRARE RQGASFAEER RVWLEEKEKV IEYQKQLQLS YVEMYQRNQQ LERRLRERGA AGGASTPTPQ HGEEKKAWTP SRLERIESTE I (328-627 aa encoded by BC038860)
Target Information
Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through a PDZ domain in ProSAP2/Shank3 and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Leucine zipper putative tumor suppressor 3; leucine zipper, putative tumor suppressor family member 3; proline rich synapse associated protein interacting protein 1; proline rich synapse associated protein interacting protein 1 (Prosapip1); ProSAP-interacting protein 1; ProSAP/Shank-interacting protein 1; ProSAPiP1
Gene Aliases: KIAA0552; LZTS3; PROSAPIP1
UniProt ID: (Human) O60299, (Mouse) A2AHG0
Entrez Gene ID: (Human) 9762, (Mouse) 241638
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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