Invitrogen

Procollagen I C-Peptide Polyclonal Antibody

3 References
View all (5) Procollagen I C-Peptide antibodies

Promotion

View available promotion(s)

Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-35380

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
View 2 publications 2 publications

Immunohistochemistry (IHC)

1:100
-

Immunocytochemistry (ICC/IF)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Sheep, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acid residues specific to the C-terminal region of human collagen 1, alpha 1 telopeptide conjugated to KLH
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

~0.15 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2552690

Product Specific Information

This antibody is predicted to react with most mammals, birds and amphibians based on 100% sequence homology.

This antibody contains enough material to conduct 10 mini-Western blots. Titrated for consistent results in Western Blot and IHC applications.

Target Information

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organix matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum depends on age and sex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: alpha-1 type 1 collagen; Alpha-1 type I collagen; alpha1(I) procollagen; C-terminal Collagen; collagen 1; collagen alpha 1 chain type I; Collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen of skin, tendon and bone, alpha-1 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; PICP; pro-alpha-1 collagen type 1; Procol; Procollagen; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; type I proalpha 1; type I procollagen alpha 1 chain; type I-alpha 1 collagen

View more View less

Gene Aliases: Col1a-1; COL1A1; Cola-1; Cola1; COLIA1; EDSC; Mov-13; Mov13; OI1; OI2; OI3; OI4

View more View less

UniProt ID: (Human) P02452, (Rat) P02454, (Mouse) P11087

View more View less

Entrez Gene ID: (Sheep) 443483, (Human) 1277, (Rat) 29393, (Mouse) 12842

View more View less

Function(s)
extracellular matrix structural constituent protein binding identical protein binding metal ion binding platelet-derived growth factor binding molecular_function
Process(es)
skeletal system development ossification blood vessel development osteoblast differentiation intramembranous ossification endochondral ossification response to nutrient visual perception sensory perception of sound response to mechanical stimulus positive regulation of epithelial to mesenchymal transition negative regulation of cell-substrate adhesion protein transport collagen fibril organization positive regulation of cell migration response to nutrient levels response to corticosteroid response to estradiol collagen biosynthetic process protein localization to nucleus tooth mineralization wound healing response to drug response to hydrogen peroxide response to peptide hormone skin development skin morphogenesis cellular response to fibroblast growth factor stimulus tooth eruption positive regulation of transcription, DNA-templated response to steroid hormone skeletal system morphogenesis embryonic skeletal system development response to cAMP response to hyperoxia face morphogenesis bone trabecula formation cartilage development involved in endochondral bone morphogenesis protein heterotrimerization cellular response to amino acid stimulus cellular response to mechanical stimulus cellular response to retinoic acid cellular response to vitamin E cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to transforming growth factor beta stimulus positive regulation of canonical Wnt signaling pathway response to fluoride cellular response to fluoride blood coagulation platelet activation extracellular matrix organization collagen catabolic process regulation of immune response leukocyte migration
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support