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Invitrogen
Procollagen IIA N-Peptide Monoclonal Antibody (003-02)
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Product Details
BTE 003-02-02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG, kappa
Class
Monoclonal
Type
Antibody
Clone
003-02
Immunogen
Recombinant expressed PIIANP.
Conjugate
Form
Liquid
Concentration
0.92 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1086822
Product Specific Information
BTE 003-02-02 is specific human PIIANP.
BTE 003-02-02 has been successfully used ELISA, and Immunohistochemistry procedures.
Epitope is located at the amino-terminal part of procollagen type IIA.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. Procollagen type II N-terminal propeptide (PIIANP) is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30 ng/mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-1 type II collagen; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; chondrocalcin; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen, type II, alpha 1
Gene Aliases: ANFH; AOM; COL11A3; COL2A1; SEDC; STL1
UniProt ID: (Human) P02458
Entrez Gene ID: (Human) 1280
skeletal system development
cartilage condensation
tissue homeostasis
endochondral ossification
chondrocyte differentiation
heart morphogenesis
proteoglycan metabolic process
central nervous system development
visual perception
sensory perception of sound
regulation of gene expression
extracellular matrix organization
collagen fibril organization
collagen catabolic process
notochord development
inner ear morphogenesis
regulation of immune response
cartilage development
palate development
limb bud formation
embryonic skeletal joint morphogenesis
cartilage development involved in endochondral bone morphogenesis
otic vesicle development
cellular response to BMP stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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