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Invitrogen
Profilin 2 Polyclonal Antibody
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Profilin 2 Antibody (PA5-21959) in IHC (P)
Profilin 2 Polyclonal Antibody detects PFN2 protein at cytoplasm on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. Profilin 2 Polyclonal Antibody (Product # PA5-21959) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-21959
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Profilin 2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153817
Product Specific Information
Recommended positive controls: A431, H1299, mouse brain, rat brain.
Predicted reactivity: Mouse (94%), Rat (91%), Chicken (93%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Profilin II; Profilin-2
Gene Aliases: D3S1319E; PFL; Pfn; PFN2
UniProt ID: (Human) P35080, (Mouse) Q9JJV2, (Rat) Q9EPC6
Entrez Gene ID: (Human) 5217, (Mouse) 18645, (Rat) 81531
negative regulation of epithelial cell migration
actin cytoskeleton organization
negative regulation of actin filament polymerization
positive regulation of actin filament polymerization
positive regulation of actin filament bundle assembly
positive regulation of ATPase activity
positive regulation of peptidyl-serine phosphorylation
protein stabilization
positive regulation of stress fiber assembly
negative regulation of ruffle assembly
regulation of synaptic vesicle exocytosis
regulation of actin filament polymerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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