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Invitrogen
Profilin 2 Polyclonal Antibody
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FIGURE: 1 / 6
Profilin 2 Antibody (PA5-79812) in ICC/IF
Immunocytochemistry analysis of PFN2 using anti-PFN2 antibody (Product # PA5-79812) . PFN2 was detected in a section of SH-SY5Y cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 5μg/mL rabbit anti-PFN2 antibody (Product # PA5-79812) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbit ... View More
Product Details
PA5-79812
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Profilin 2 (125-140aa NKKAYSMAKYLRDSGF).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746927
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta tissue, rat brain tissue, mouse brain tissue. IHC: human tonsil tissue, human intestinal cancer tissue. ICC/IF: SH-SY5Y cell. Flow: A431 cell.
Target Information
Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Profilin II; Profilin-2
Gene Aliases: D3S1319E; PFL; Pfn; PFN2
UniProt ID: (Human) P35080, (Mouse) Q9JJV2, (Rat) Q9EPC6
Entrez Gene ID: (Human) 5217, (Mouse) 18645, (Rat) 81531
negative regulation of epithelial cell migration
actin cytoskeleton organization
negative regulation of actin filament polymerization
positive regulation of actin filament polymerization
positive regulation of actin filament bundle assembly
positive regulation of ATPase activity
positive regulation of peptidyl-serine phosphorylation
protein stabilization
positive regulation of stress fiber assembly
negative regulation of ruffle assembly
regulation of synaptic vesicle exocytosis
regulation of actin filament polymerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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