Invitrogen

Prolactin Monoclonal Antibody (6F11)

Prolactin Antibody in Immunohistochemistry (IHC)

FIGURE: 1 / 3

Prolactin Antibody (MA1-10597) in IHC

Bosnian journal of basic medical sciences 2021 - FIGURE 3 The effect of L-dopa on the expression of PRL and Syt-IV. (A) Densitometric quantification of PRL immunosignal shows that the expression of PRL was significantly higher in treatment groups that received E2 (N = 10) compared to healthy animals (N = 5). Treatment with L-dopa did not have a significant effect on the expression of PRL. (B) Densitometric quantification of Syt-IV immunosignal shows that ... View More

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Product Details

MA1-10597

Applications

Tested Dilution

Publications

Western Blot (WB)

1-10 µg/mL

View 1 publication 1 publication

Immunohistochemistry (IHC)

1-10 µg/mL

View 2 publications 2 publications

ELISA (ELISA)

1-10 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Non-human primate, Sheep, Rat

Published species

Human, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

6F11

Immunogen

Sheep and human Prolactin.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2284419

Product Specific Information

MA1-10597 detects Prolactin from human, mouse, rat, bovine, ovine and squirrel monkey samples.

MA1-10597 has been successfully used in ELISA, immunohistochemistry, and Western blot applications.

The MA1-10597 immunogen is sheep and human Prolactin.

Target Information

Prolactin (PRL) is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Intranasal 15d-PGJ2 inhibits the growth of rat lactotroph pituitary neuroendocrine tumors by inducing PPARγ-dependent apoptotic and autophagic cell death.

Frontiers in neuroscience

Li Z,Chen L,Zhang D,Huang X,Yang J,Li W,Wang C,Meng X,Huang G

MA1-10597 was used in ELISA to find that intranasal 15d-PGJ2, an endogenous PPARγ agonist, resulted in growth suppression of Fischer 344 rat lactotroph PitNETs induced by subcutaneous implantation with a mini-osmotic pump containing estradiol.

Wed May 31 00:00:00 UTC 2023

Effects of L-dopa on expression of prolactin and synaptotagmin IV in 17-beta-estradiol-induced prolactinomas of ovariectomized hemiparkinsonian rats.

Bosnian journal of basic medical sciences

Zorovic M,Kolmančič K,Živin M

Published figure using Prolactin monoclonal antibody (Product # MA1-10597) in Immunohistochemistry

Wed Dec 01 00:00:00 UTC 2021

Local production of prolactin in lesions may play a pathogenic role in psoriatic patients and imiquimod-induced psoriasis-like mouse model.

Experimental dermatology

Yang H,Li X,Xue F,Xia Q,Zhao X,Wang D,Chen L,Cao H,Xu H,Shen X,Yuan W,Zhao X,Shi R,Zheng J

MA1-10597 was used in Western Blotting to suggest that local production of PRL is the main resource of PRL in skin lesions and may play an important role in skin inflammatory of psoriasis.

Thu Nov 01 00:00:00 UTC 2018

Hormone receptor expressions and proliferation markers in postmenopausal endometrial polyps.

Gynecologic and obstetric investigation

Inceboz US,Nese N,Uyar Y,Ozcakir HT,Kurtul O,Baytur YB,Kandiloglu AR,Caglar H,Fraser IS

MA1-10597 was used in immunohistochemistry to study the expression of hormone receptors and proliferative markers in postmenopausal endometrial polyps

Tue Jan 30 00:00:00 UTC 2007

Bioinformatics

Protein Aliases: decidual prolactin; growth hormone A1; Human prolactin; PRL; Prolactin; prolactin family 1, subfamily a, member 1

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Gene Aliases: AV290867; BOS_21850; GHA1; PRL; Prl1a1; PRLB; PRLSD1; Prol; RATPRLSD1; RNPROL

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UniProt ID: (Human) P01236, (Sheep) P01240, (Bovine) P01239, (Rat) P01237

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Entrez Gene ID: (Human) 5617, (Sheep) 443317, (Bovine) 280901, (Mouse) 19109, (Rat) 24683

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Function(s)

prolactin receptor binding hormone activity protein binding

Process(es)

cell surface receptor signaling pathway female pregnancy lactation cell proliferation regulation of multicellular organism growth cellular protein metabolic process positive regulation of JAK-STAT cascade JAK-STAT cascade involved in growth hormone signaling pathway STAT protein import into nucleus positive regulation of cell proliferation regulation of ossification mammary gland development maternal behavior regulation of JAK-STAT cascade positive regulation of epithelial cell proliferation parturition response to nutrient circadian rhythm response to organic cyclic compound response to estradiol response to lipopolysaccharide cellular response to hormone stimulus multicellular organismal response to stress response to drug ovulation cycle response to ethanol

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Prolactin Monoclonal Antibody (6F11)

Prolactin Antibody (MA1-10597) in IHC

Product Details

MA1-10597

Western Blot (WB)

Immunohistochemistry (IHC)

ELISA (ELISA)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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