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Invitrogen
Prostaglandin E Receptor EP1 Polyclonal Antibody
FIGURE: 1 / 1
Prostaglandin E Receptor EP1 Antibody (PA5-88476) in WB
Western blot analysis of Prostaglandin E Receptor EP1 in extracts of mouse pancreas. Samples were incubated with Prostaglandin E Receptor EP1 Polyclonal antibody (Product # PA5-88476) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-88476
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PGE receptor EP1 (PGE receptor EP1 (PTGER1)) (NP_0009462)
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804938
Product Specific Information
Immunogen sequence: VGIMVVSCIC WSPMLVLVAL AVGGWSSTSL QRPLFLAVRL ASWNQILDPW VYILLRQAVL RQLLRLLPPR AGAKGGPAGL GLTPSAWEAS SLRSSRHSGL S; Positive Samples: Mouse pancreas; Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PGE receptor EP1 subtype; PGE2 receptor EP1 subtype; Prostaglandin E2 receptor EP1 subtype; Prostanoid EP1 receptor
Gene Aliases: 42kDa; EP1; Ptger1; Ptgerep1
UniProt ID: (Mouse) P35375
Entrez Gene ID: (Mouse) 19216
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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