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Invitrogen
Protein C (Active) Monoclonal Antibody (PC107)
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Product Details
MA5-49088
Product Specifications
Species Reactivity
Human
Host/Isotype
Rat
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PC107
Immunogen
Monoclonal antibody PC107 is specific for activated Protein C (APC
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
Protein G
Storage buffer
PBS with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3091126
Product Specific Information
The monoclonal antibody PC107 is specific for activated human protein C (APC) and it lacks reactivity for Protein C. The monoclonal antibody recognizes the light chain of the APC molecule.
Target Information
Protein C is a protein that plays a crucial role in the regulation of blood clotting. It is a vitamin K-dependent serine protease that is activated by thrombin, a protein that promotes blood clotting. Once activated, protein C proteolytically cleaves and inactivates factors V and VIII, which are essential for the formation of blood clots. This process helps to prevent excessive blood clotting and maintain the normal flow of blood through the body. In addition to its anticoagulant function, protein C has also been shown to have anti-inflammatory and cytoprotective properties, suggesting that it may have a broader role in maintaining vascular health.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Active Protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; prepro-protein C; protein C (inactivator of coagulation factors Va and VIIIa); type I protein C; Vitamin K-dependent protein C
Gene Aliases: APC; PC; PROC; PROC1; THPH3; THPH4
UniProt ID: (Human) P04070
Entrez Gene ID: (Human) 5624
signal peptide processing
proteolysis
ER to Golgi vesicle-mediated transport
blood coagulation
peptidyl-glutamic acid carboxylation
negative regulation of blood coagulation
negative regulation of apoptotic process
negative regulation of inflammatory response
negative regulation of coagulation
leukocyte migration
positive regulation of establishment of endothelial barrier
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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