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QED Bioscience
Protein Tyrosine phosphatase Receptor F (PTPRF) Monoclonal Antibody (S165-38)
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FIGURE: 1 / 3
Protein Tyrosine phosphatase Receptor F (PTPRF) Antibody (56579-100UG) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-LAR/PTPRF Monoclonal Antibody, Clone S165-38 (56579). Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-LAR/PTPRF Monoclonal Antibody (56579) at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloid... View More
Product Details
56579-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
S165-38
Immunogen
Fusion protein corresponding to aa 1315-1607 (cytoplasmic C-terminus) of human PTPRF. This sequence is 97
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Target Information
Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ43335; FLJ45062; FLJ45567; LAR; LAR protein; LCA homolog; LCA-homolog; leukocyte antigen-related (LAR) PTP receptor; leukocyte antigen-related tyrosine phosphatase; Leukocyte common antigen related; protein tyrosine phosphatase receptor-type F; protein tyrosine phosphatase, receptor type, F polypeptide; PTPRF protein; receptor-linked protein-tyrosine phosphatase LAR; Receptor-type tyrosine-protein phosphatase F
Gene Aliases: AA591035; BNAH2; LAR; LARFN5C; LARS; PTPRF; RPTP-LAR
UniProt ID: (Human) P10586, (Rat) Q64604, (Mouse) A2A8L5
Entrez Gene ID: (Human) 5792, (Rat) 360406, (Mouse) 19268
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
heparin binding
protein complex binding
chondroitin sulfate proteoglycan binding
insulin receptor binding
receptor tyrosine kinase binding
phosphate ion binding
phosphoprotein phosphatase activity
hydrolase activity
phosphatase activity
negative regulation of cytokine-mediated signaling pathway
protein dephosphorylation
homophilic cell adhesion via plasma membrane adhesion molecules
nervous system development
negative regulation of cell proliferation
regulation of neuron projection development
cell migration
neuron projection regeneration
negative regulation of cell projection organization
peptidyl-tyrosine dephosphorylation
negative regulation of epidermal growth factor receptor signaling pathway
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of insulin receptor signaling pathway
regulation of axon regeneration
positive regulation of dendrite morphogenesis
regulation of synapse structure or activity
negative regulation of neurotrophin TRK receptor signaling pathway
negative regulation of receptor binding
cell adhesion
signal transduction
dephosphorylation
transmembrane receptor protein tyrosine phosphatase signaling pathway
chemical synaptic transmission
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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