Product References
Regulation of the apico-basolateral trafficking polarity of the homologous copper-ATPases ATP7A and ATP7B.
Journal of cell science
Mishra M,Saha S,Maji S,Rodriguez-Boulan E,Schreiner R,Gupta A
71-5300 was used in Immunocytochemistry to find that the AP-1A complex provides directionality and TGN retention for both Cu-ATPases, whereas the AP-1B complex governs copper-independent trafficking of ATP7B solely.
Fri Mar 01 00:00:00 UTC 2024
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.
Journal of cell science
Wilson B,Flett C,Gemperle J,Lawless C,Hartshorn M,Hinde E,Harrison T,Chastney M,Taylor S,Allen J,Norman JC,Zacharchenko T,Caswell PT
71-5300 was used in Western Blotting and Immunocytochemistry to identify new endocytic recycling machinery associated with Rab4, Rab11 and Rab25 that regulates cancer cell migration in the 3D matrix.
Thu Jun 15 00:00:00 UTC 2023
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.
Journal of cell science
Wilson B,Flett C,Gemperle J,Lawless C,Hartshorn M,Hinde E,Harrison T,Chastney M,Taylor S,Allen J,Norman JC,Zacharchenko T,Caswell PT
71-5300 was used in Western Blotting and Immunocytochemistry to identify new endocytic recycling machinery associated with Rab4, Rab11 and Rab25 that regulates cancer cell migration in the 3D matrix.
Thu Jun 15 00:00:00 UTC 2023
Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis.
Cellular and molecular life sciences : CMLS
Pust S,Brech A,Wegner CS,Stenmark H,Haglund K
71-5300 was used in Immunocytochemistry to propose that ALIX, TSG101 and CHMP4B are associated with endosomal vesicles transported on microtubules by kinesin-1 to the cytokinetic bridge and midbody, thereby contributing to their function in abscission.
Mon Jul 31 00:00:00 UTC 2023
Coxiella burnetii Plasmid Effector B Promotes LC3-II Accumulation and Contributes To Bacterial Virulence in a SCID Mouse Model.
Infection and immunity
Fu M,Zhang J,Zhao M,Zhang S,Dai L,Ouyang X,Yu Y,Wen B,Zhou D,Sun Y,Jiao J,Xiong X
71-5300 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot to suggest that CpeB promotes C. burnetii virulence by inducing LC3-II accumulation via a pathway involving Rab11a.
Thu Jun 16 00:00:00 UTC 2022
The endocytic recycling compartment serves as a viral factory for hepatitis E virus.
Cellular and molecular life sciences : CMLS
Bentaleb C,Hervouet K,Montpellier C,Camuzet C,Ferrié M,Burlaud-Gaillard J,Bressanelli S,Metzger K,Werkmeister E,Ankavay M,Janampa NL,Marlet J,Roux J,Deffaud C,Goffard A,Rouillé Y,Dubuisson J,Roingeard P,Aliouat-Denis CM,Cocquerel L
71-5300 was used in Immunocytochemistry to show that hepatitis E virus (HEV) hijacks the endocytic recycling compartment and forms a membrane network of vesicular and tubular structures that might be the hallmark of HEV infection.
Sat Dec 03 00:00:00 UTC 2022
Restoring Oat Nanoparticles Mediated Brain Memory Function of Mice Fed Alcohol by Sorting Inflammatory Dectin-1 Complex Into Microglial Exosomes.
Small (Weinheim an der Bergstrasse, Germany)
Xu F,Mu J,Teng Y,Zhang X,Sundaram K,Sriwastva MK,Kumar A,Lei C,Zhang L,Liu QM,Yan J,McClain CJ,Merchant ML,Zhang HG
71-5300 was used in Western Blotting to find that oral administration of oatN inhibits brain inflammation and improves brain memory function of mice that are fed alcohol.
Tue Feb 01 00:00:00 UTC 2022
PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity.
EMBO reports
Anquetil T,Solinhac R,Jaffre A,Chicanne G,Viaud J,Darcourt J,Orset C,Geuss E,Kleinschnitz C,Vanhaesebroeck B,Vivien D,Hnia K,Larrue V,Payrastre B,Gratacap MP
71-5300 was used in Immunocytochemistry-immunoflourescence to study the role of PI3KC2β in endothelial permeability and endosomal trafficking in vitro and in vivo in ischemic stroke.
Fri Jun 04 00:00:00 UTC 2021
Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.
The Journal of cell biology
Chandrakumar AA,Coyaud É,Marshall CB,Ikura M,Raught B,Rottapel R
71-5300 was used in Western Blot, Immunohistochemistry to show a mechanism of regulation for Rab11a GTPase activation during epithelial cell polarity involving protein-protein interactions and post-translational modifications involving a complex interplay between RNF146, Tankyrases, and SH3BP5 paralogues.
Mon Jul 05 00:00:00 UTC 2021
Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.
The Journal of cell biology
Chandrakumar AA,Coyaud É,Marshall CB,Ikura M,Raught B,Rottapel R
71-5300 was used in Western Blot, Immunohistochemistry to show a mechanism of regulation for Rab11a GTPase activation during epithelial cell polarity involving protein-protein interactions and post-translational modifications involving a complex interplay between RNF146, Tankyrases, and SH3BP5 paralogues.
Mon Jul 05 00:00:00 UTC 2021
Cyclophilin A regulates secretion of tumour-derived extracellular vesicles.
Translational oncology
Wu Y,Brennan K,Fernández AB,Mc Gee MM
71-5300 was used in Immunocytochemistry to investigate extracellular vesicle secretions in cancer.
Sun Aug 01 00:00:00 UTC 2021
EBI2 Is Temporarily Upregulated in MO3.13 Oligodendrocytes during Maturation and Regulates Remyelination in the Organotypic Cerebellar Slice Model.
International journal of molecular sciences
Velasco-Estevez M,Koch N,Klejbor I,Laurent S,Dev KK,Szutowicz A,Sailer AW,Rutkowska A
71-5300 was used in Immunocytochemistry to study the role of EB12 in regulating neuronal rehabilitative processes.
Wed Apr 21 00:00:00 UTC 2021
Analysis of the intracellular traffic of IgG in the context of Down syndrome (trisomy 21).
Scientific reports
Cejas RB,Tamaño-Blanco M,Blanco JG
71-5300 was used in Western Blot, Immunocytochemistry to analyse the intracellular traffic of IgG mediated by the human neonatal Fc receptor (FcRn) in fibroblast cell lines with trisomy 21.
Wed May 26 00:00:00 UTC 2021
Analysis of the intracellular traffic of IgG in the context of Down syndrome (trisomy 21).
Scientific reports
Cejas RB,Tamaño-Blanco M,Blanco JG
71-5300 was used in Western Blot, Immunocytochemistry to analyse the intracellular traffic of IgG mediated by the human neonatal Fc receptor (FcRn) in fibroblast cell lines with trisomy 21.
Wed May 26 00:00:00 UTC 2021
Maduramicin induces cardiotoxicity via Rac1 signaling-independent methuosis in H9c2 cells.
Journal of applied toxicology : JAT
Gao X,Ji C,Wang J,Song X,Zuo R,Zhang J,Chen X,Ji H,Peng L,Guo D,Jiang S
71-5300 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot to show that maduramicin induces methuosis in H9c2 cells via Rac-1 signaling-independent seriously cytoplasmic vacuolization.
Wed Dec 01 00:00:00 UTC 2021
Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.
Acta neuropathologica
Martin S,Smolders S,Van den Haute C,Heeman B,van Veen S,Crosiers D,Beletchi I,Verstraeten A,Gossye H,Gelders G,Pals P,Hamouda NN,Engelborghs S,Martin JJ,Eggermont J,De Deyn PP,Cras P,Baekelandt V,Vangheluwe P,Van Broeckhoven C
71-5300 was used in Immunocytochemistry-immunoflourescence to show risk of Parkinson's disease is increased by recessive loss of function mutations in ATP10B.
Mon Jun 01 00:00:00 UTC 2020
Correlated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Carter SD,Mamede JI,Hope TJ,Jensen GJ
71-5300 was used in Immunocytochemistry to apply cryogenic correlated light and electron microscopy, combined with electron cryo-tomography, to intact mammalian cells expressing YFP-rhTRIM5α and found the presence of hexagonal nets whose arm lengths were similar to those of the hexagonal nets formed by purified TRIM5α in vitro.
Tue Nov 24 00:00:00 UTC 2020
A modified lysosomal organelle mediates nonlytic egress of reovirus.
The Journal of cell biology
Fernández de Castro I,Tenorio R,Ortega-González P,Knowlton JJ,Zamora PF,Lee CH,Fernández JJ,Dermody TS,Risco C
71-5300 was used in Immunocytochemistry to show that reovirus uses a previously undescribed, membrane-engaged, nonlytic egress mechanism and highlights a potential new target for therapeutic intervention.
Mon Jul 06 00:00:00 UTC 2020
The Rab5-Rab11 Endosomal Pathway is Required for BDNF-Induced CREB Transcriptional Regulation in Hippocampal Neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
González-Gutiérrez A,Lazo OM,Bronfman FC
71-5300 was used in Immunocytochemistry-immunoflourescence to uncover the cellular requirements that central neurons possess to integrate the plasma membrane into nuclear signaling in neurons.
Wed Oct 14 00:00:00 UTC 2020
Herpes Simplex Virus Entry by a Nonconventional Endocytic Pathway.
Journal of virology
Tebaldi G,Pritchard SM,Nicola AV
71-5300 was used in Western Blot to characterize Herpes simplex virus 1 entry by endocytosis.
Mon Nov 23 00:00:00 UTC 2020
Membrane Dynamics and Organization of the Phagocyte NADPH Oxidase in PLB-985 Cells.
Frontiers in cell and developmental biology
Joly J,Hudik E,Lecart S,Roos D,Verkuijlen P,Wrona D,Siler U,Reichenbach J,Nüsse O,Dupré-Crochet S
71-5300 was used in Immunocytochemistry-immunoflourescence to suggest a role for p47phox and possibly ROS production in NOX2 recruitment at the phagosome.
Thu Dec 31 00:00:00 UTC 2020
The atypical Rho GTPase RhoU interacts with intersectin-2 to regulate endosomal recycling pathways.
Journal of cell science
Gubar O,Croisé P,Kropyvko S,Gryaznova T,Tóth P,Blangy A,Vitale N,Rynditch A,Gasman S,Ory S
71-5300 was used in Immunocytochemistry-immunoflourescence to identify intersectins (ITSNs) as new binding partners for RhoU and showed that the second PxxP motif at the N terminus of RhoU mediated interactions with the SH3 domains of ITSNs.
Thu Aug 27 00:00:00 UTC 2020
Heterogeneity in the endocytic capacity of individual macrophage in a population determines its subsequent phagocytosis, infectivity and subcellular trafficking.
Traffic (Copenhagen, Denmark)
Sachdeva K,Goel M,Sundaramurthy V
71-5300 was used in Immunocytochemistry to demonstrate that the variance in macrophage endocytic capacity results in phagocytosis heterogeneity.
Sat Aug 01 00:00:00 UTC 2020
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
Neurobiology of disease
Teoh J,Subramanian N,Pero ME,Bartolini F,Amador A,Kanber A,Williams D,Petri S,Yang M,Allen AS,Beal J,Haut SR,Frankel WN
71-5300 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot to demonstrate that the altered endosome composition and decreased neuronal surface GABAAR results suggests a mechanism whereby impaired neuronal inhibition leads to seizure susceptibility.
Sat Feb 01 00:00:00 UTC 2020
CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration.
Science signaling
Ghosh M,Lo R,Ivic I,Aguilera B,Qendro V,Devarakonda C,Shapiro LH
71-5300 was used in Immunocytochemistry-Immunofluorescence to explore the role for CD13 in regulating fundamental cellular processes, such as cell migration.
Tue Apr 30 00:00:00 UTC 2019
ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Rawat V,Wang S,Sima J,Bar R,Liraz O,Gundimeda U,Parekh T,Chan J,Johansson JO,Tang C,Chui HC,Harrington MG,Michaelson DM,Yassine HN
71-5300 was used in Immunocytochemistry-immunoflourescence to provide insights into the ATP binding cassette A1 interactome and ApoE protein lipidation and aggregation.
Wed Nov 27 00:00:00 UTC 2019
The LMTK1-TBC1D9B-Rab11A Cascade Regulates Dendritic Spine Formation via Endosome Trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nishino H,Saito T,Wei R,Takano T,Tsutsumi K,Taniguchi M,Ando K,Tomomura M,Fukuda M,Hisanaga SI
71-5300 was used in Western Blotting to investigate the role of LMTK1 in spine formation.
Wed Nov 27 00:00:00 UTC 2019
The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3.
Journal of cell science
Furlong RM,Lindsay A,Anderson KE,Hawkins PT,Sullivan AM,O'Neill C
71-5300 was used in Immunocytochemistry to demonstrate a new role for PINK1 as a primary upstream activator of Akt via PINK1 kinase-dependent regulation of its primary activator PI(3,4,5)P3, providing novel mechanistic information on how loss of PINK1 impairs Akt signalling in PD.
Tue Oct 22 00:00:00 UTC 2019
Cdc42 negatively regulates endocytosis during apical membrane maintenance in live animals.
Molecular biology of the cell
Shitara A,Malec L,Ebrahim S,Chen D,Bleck C,Hoffman MP,Weigert R
71-5300 was used in Immunocytochemistry-immunoflourescence to determine the role of the small GTPase Cdc42 in the regulation of homeostasis of the intercellular canaliculi.
Fri Feb 01 00:00:00 UTC 2019
Structural basis of guanine nucleotide exchange for Rab11 by SH3BP5.
Life science alliance
Goto-Ito S,Morooka N,Yamagata A,Sato Y,Sato K,Fukai S
71-5300 was used in Immunocytochemistry-immunoflourescence to elucidate the structural basis of guanine nucleotide exchange for Rab11 by SH3BP5.
Mon Apr 01 00:00:00 UTC 2019
Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2.
The Journal of biological chemistry
Fred SM,Laukkanen L,Brunello CA,Vesa L,Göös H,Cardon I,Moliner R,Maritzen T,Varjosalo M,Casarotto PC,Castrén E
71-5300 was used in Immunocytochemistry-immunoflourescence to suggest that disruption of the TRKB:AP2M interaction is a common mechanism underlying TRKB activation by several chemically diverse antidepressants.
Fri Nov 29 00:00:00 UTC 2019
LC3-positive structures are prominent in autophagy-deficient cells.
Scientific reports
Runwal G,Stamatakou E,Siddiqi FH,Puri C,Zhu Y,Rubinsztein DC
71-5300 was used in Immunocytochemistry to question the reliability of LC3-immunofluorescence assays in cells with compromised autophagy.
Fri Jul 12 00:00:00 UTC 2019
Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites.
Nature communications
Alenquer M,Vale-Costa S,Etibor TA,Ferreira F,Sousa AL,Amorim MJ
71-5300 was used in Immunocytochemistry-immunoflourescence to elucidate how influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites.
Tue Apr 09 00:00:00 UTC 2019
Expansion and contraction of the umbrella cell apical junctional ring in response to bladder filling and voiding.
Molecular biology of the cell
Eaton AF,Clayton DR,Ruiz WG,Griffiths SE,Rubio ME,Apodaca G
71-5300 was used in Immunohistochemistry to indicate that a mechanism by which the umbrella cells retain continuity during cyclical changes in volume is the expansion and contraction of their AJR, processes regulated by the actomyosin cytoskeleton and membrane trafficking events.
Mon Jul 22 00:00:00 UTC 2019
SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors.
Nature communications
Koike S,Jahn R
71-5300 was used in Western Blotting to conclude that SNAREs use a combinatorial code for recruiting tethering factors, revealing a key function in targeting that is independent of SNARE pairing during fusion.
Mon Apr 08 00:00:00 UTC 2019
Impaired Transferrin Receptor Palmitoylation and Recycling in Neurodegeneration with Brain Iron Accumulation.
American journal of human genetics
Drecourt A,Babdor J,Dussiot M,Petit F,Goudin N,Garfa-Traoré M,Habarou F,Bole-Feysot C,Nitschké P,Ottolenghi C,Metodiev MD,Serre V,Desguerre I,Boddaert N,Hermine O,Munnich A,Rötig A
71-5300 was used in Immunocytochemistry-immunoflourescence to study how neurodegeneration with brain iron accumulation (NBIA)-associated mutations trigger iron overload.
Thu Feb 01 00:00:00 UTC 2018
SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2.
EMBO reports
Søreng K,Munson MJ,Lamb CA,Bjørndal GT,Pankiv S,Carlsson SR,Tooze SA,Simonsen A
71-5300 was used in Western Blotting to show that the membrane remodelling protein SNX18, previously identified as a positive regulator of autophagy, regulates ATG9A trafficking from recycling endosomes.
Sun Apr 01 00:00:00 UTC 2018
The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation.
Cellular and molecular gastroenterology and hepatology
Cox CM,Lu R,Salcin K,Wilson JM
Mon Mar 14 00:00:00 UTC 2022
Engaging myosin VI tunes motility, morphology and identity in endocytosis.
Traffic (Copenhagen, Denmark)
Ritt M,Sivaramakrishnan S
71-5300 was used in Immunocytochemistry to show that synthetic engagement of myosin VI motility is sufficient to alter organelle homeostasis in the endocytic pathway.
Mon Jun 04 00:00:00 UTC 2018
Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes.
Molecular metabolism
Rödiger M,Werno MW,Wilhelmi I,Baumeier C,Hesse D,Wettschureck N,Offermanns S,Song K,Krauß M,Schürmann A
71-5300 was used in Immunocytochemistry-immunoflourescence to demonstrate the role of the trans-Golgi localised monomeric GTPase ARFRP1 in endosomal-mediated vesicle trafficking of mature adipocytes.
Thu Feb 01 00:00:00 UTC 2018
Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes.
Molecular metabolism
Rödiger M,Werno MW,Wilhelmi I,Baumeier C,Hesse D,Wettschureck N,Offermanns S,Song K,Krauß M,Schürmann A
71-5300 was used in Immunocytochemistry-immunoflourescence to demonstrate the role of the trans-Golgi localised monomeric GTPase ARFRP1 in endosomal-mediated vesicle trafficking of mature adipocytes.
Thu Feb 01 00:00:00 UTC 2018
Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling.
Biology of the cell
Nakashima M,Watanabe M,Uchimaru K,Horie R
71-5300 was used in Immunocytochemistry-immunofluorescence to evaluate CHO cells expressing CD30L fused to mCherry and HeLa cells expressing CD30 fused to GFP to improve CD30 signalling.
Tue May 01 00:00:00 UTC 2018
Brain-Derived Neurotrophic Factor (BDNF) Regulates Rab5-Positive Early Endosomes in Hippocampal Neurons to Induce Dendritic Branching.
Frontiers in cellular neuroscience
Moya-Alvarado G,Gonzalez A,Stuardo N,Bronfman FC
71-5300 was used in Western Blotting to study the regulation of Rab5-positive endosomes by brain-derived neurotrophic factor at different levels, including dynamic, activity and protein levels in hippocampal neurons.
Thu Oct 01 00:00:00 UTC 2020
Combining high-pressure freezing with pre-embedding immunogold electron microscopy and tomography.
Traffic (Copenhagen, Denmark)
Hess MW,Vogel GF,Yordanov TE,Witting B,Gutleben K,Ebner HL,de Araujo MEG,Filipek PA,Huber LA
71-5300 was used in Immunomicroscopy to describe here a specimen preparation and labeling protocol for animal cell cultures, which represents a novel blend of specifically adapted versions of established techniques.
Wed Aug 01 00:00:00 UTC 2018
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation.
Nature cell biology
O'Farrell F,Lobert VH,Sneeggen M,Jain A,Katheder NS,Wenzel EM,Schultz SW,Tan KW,Brech A,Stenmark H,Rusten TE
71-5300 was used in Immunocytochemistry-immunofluorescence to define a CIII-PI3K-regulated endosomal signalling platform from which LKB1 directs epithelial polarity, the dysregulation of which endows LKB1 with tumour-promoting properties.
Fri Dec 01 00:00:00 UTC 2017
Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes.
Autophagy
Li J,Chen Z,Stang MT,Gao W
71-5300 was used in Immunocytochemistry-immunoflourescence to study the membrane source for autophagosome biogenesis.
Wed Feb 01 00:00:00 UTC 2017
Hedgehog signaling regulates ciliary localization of mouse odorant receptors.
Proceedings of the National Academy of Sciences of the United States of America
Maurya DK,Bohm S,Alenius M
71-5300 was used in Immunohistochemistry to define a physiological function of Hedgehog signalling in olfaction and a link between olfaction and the ciliary compartments for Hedgehog signalling.
Tue Oct 31 00:00:00 UTC 2017
The Atypical Receptor CCRL2 (C-C Chemokine Receptor-Like 2) Does Not Act As a Decoy Receptor in Endothelial Cells.
Frontiers in immunology
Mazzotti C,Gagliostro V,Bosisio D,Del Prete A,Tiberio L,Thelen M,Sozzani S
71-5300 was used in Immunocytochemistry-immunoflourescence to confirm the ability of C-C chemokine receptor-like 2 (CCRL2) to bind chemerin, the only recognised ligand, but excluded the ability of CCRL2 to perform scavenging.
Wed Nov 20 00:00:00 UTC 2019
Gb3-binding lectins as potential carriers for transcellular drug delivery.
Expert opinion on drug delivery
Müller SK,Wilhelm I,Schubert T,Zittlau K,Imberty A,Madl J,Eierhoff T,Thuenauer R,Römer W
71-5300 was used in immunocytochemistry to assess lectins recognizing the glycosphingolipid globotriaosylceramide as carriers for transcytotic drug delivery
Wed Feb 01 00:00:00 UTC 2017
PtdIns3P controls mTORC1 signaling through lysosomal positioning.
The Journal of cell biology
Hong Z,Pedersen NM,Wang L,Torgersen ML,Stenmark H,Raiborg C
71-5300 was used in Immunocytochemistry to study the mechanism by which rapamycin complex 1 is activated by lysosome positioning and by amino acid-stimulated production of phosphatidylinositol 3-phosphate by the lipid kinase VPS34/PIK3C3.
Mon Dec 04 00:00:00 UTC 2017
Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport.
PLoS pathogens
Guichard A,Jain P,Moayeri M,Schwartz R,Chin S,Zhu L,Cruz-Moreno B,Liu JZ,Aguilar B,Hollands A,Leppla SH,Nizet V,Bier E
71-5300 was used in Western Blotting to examine the mechanisms of Rab11 inhibition by oedema factor.
Fri Sep 01 00:00:00 UTC 2017
Abnormal Rab11-Rab8-vesicles cluster in enterocytes of patients with microvillus inclusion disease.
Traffic (Copenhagen, Denmark)
Vogel GF,Janecke AR,Krainer IM,Gutleben K,Witting B,Mitton SG,Mansour S,Ballauff A,Roland JT,Engevik AC,Cutz E,Müller T,Goldenring JR,Huber LA,Hess MW
71-5300 was used in Immunohistochemistry to study the identity and the pathophysiological significance of secretory granules in microvillus inclusion disease.
Sat Jul 01 00:00:00 UTC 2017
Endocytic turnover of Rab8 controls cell polarization.
Journal of cell science
Vidal-Quadras M,Holst MR,Francis MK,Larsson E,Hachimi M,Yau WL,Peränen J,Martín-Belmonte F,Lundmark R
715300 was used in western blot to investigate the interaction between GRAF1 and RAB8
Wed Mar 15 00:00:00 UTC 2017
EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment.
Journal of cell science
Eva R,Koseki H,Kanamarlapudi V,Fawcett JW
71-5300 was used in Immunocytochemistry to identify a novel regulator of selective axon transport and regeneration, the ARF6 guanine-nucleotide-exchange factor EFA6.
Wed Nov 01 00:00:00 UTC 2017
KIF13A mediates trafficking of influenza A virus ribonucleoproteins.
Journal of cell science
Ramos-Nascimento A,Kellen B,Ferreira F,Alenquer M,Vale-Costa S,Raposo G,Delevoye C,Amorim MJ
71-5300 was used in Immunocytochemistry-immunoflourescence to identify KIF13A as the first molecular motor to efficiently transport vRNP-Rab11 vesicles during infection with influenza A.
Fri Dec 01 00:00:00 UTC 2017
Selective rab11 transport and the intrinsic regenerative ability of CNS axons.
eLife
Koseki H,Donegá M,Lam BY,Petrova V,van Erp S,Yeo GS,Kwok JC,Ffrench-Constant C,Eva R,Fawcett JW
71-5300 was used in Immunocytochemistry-immunoflourescence to show that the decline of intrinsic axon regenerative ability is associated with selective exclusion of key molecules.
Tue Aug 08 00:00:00 UTC 2017
Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells.
Nature communications
Matsudaira T,Mukai K,Noguchi T,Hasegawa J,Hatta T,Iemura SI,Natsume T,Miyamura N,Nishina H,Nakayama J,Semba K,Tomita T,Murata S,Arai H,Taguchi T
71-5300 was used in Immunocytochemistry to study the link between endosomal phosphatidylserine and cell proliferation.
Wed Nov 01 00:00:00 UTC 2017
Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells.
Nature communications
Matsudaira T,Mukai K,Noguchi T,Hasegawa J,Hatta T,Iemura SI,Natsume T,Miyamura N,Nishina H,Nakayama J,Semba K,Tomita T,Murata S,Arai H,Taguchi T
71-5300 was used in Immunocytochemistry to study the link between endosomal phosphatidylserine and cell proliferation.
Wed Nov 01 00:00:00 UTC 2017
Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo.
Hepatology (Baltimore, Md.)
Porat-Shliom N,Tietgens AJ,Van Itallie CM,Vitale-Cross L,Jarnik M,Harding OJ,Anderson JM,Gutkind JS,Weigert R,Arias IM
715300 was used in immunohistochemistry to use transgenic mice to clarify the role of LKB1 in the maintenance of functional tight junction
Sat Oct 01 00:00:00 UTC 2016
Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.
Proceedings of the National Academy of Sciences of the United States of America
Dustrude ET,Moutal A,Yang X,Wang Y,Khanna M,Khanna R
71-5300 was used in immunocytochemistry to study NaV1.7 trafficking
Tue Dec 27 00:00:00 UTC 2016
Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Villarroel-Campos D,Henríquez DR,Bodaleo FJ,Oguchi ME,Bronfman FC,Fukuda M,Gonzalez-Billault C
715300 was used in western blot to investigate mechanisms involved in Rab35-mediated axonal elongation
Wed Jul 06 00:00:00 UTC 2016
Influenza A virus ribonucleoproteins modulate host recycling by competing with Rab11 effectors.
Journal of cell science
Vale-Costa S,Alenquer M,Sousa AL,Kellen B,Ramalho J,Tranfield EM,Amorim MJ
71-5300 was used in Immunocytochemistry-immunoflourescence to describe that vRNP binding to recycling endosome vesicles impairs its function, by competing with family-interacting-proteins for Rab11 binding.
Fri Apr 15 00:00:00 UTC 2016
NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling.
Journal of cell science
Chamberland JP,Antonow LT,Dias Santos M,Ritter B
71-5300 was used in immunocytochemistry to determine control of clathrin coat recruitment to early endosomes for fast endocytic recycling by NECAP2
Fri Jul 01 00:00:00 UTC 2016
Role of CD34 family members in lumen formation in the developing kidney.
Developmental biology
Yang Z,Zimmerman SE,Tsunezumi J,Braitsch C,Trent C,Bryant DM,Cleaver O,González-Manchón C,Marciano DK
715300 was used in immunohistochemistry - paraffin section to show that Endoglycan is a pre-luminal marker
Sat Oct 01 00:00:00 UTC 2016
Activation of STING requires palmitoylation at the Golgi.
Nature communications
Mukai K,Konno H,Akiba T,Uemura T,Waguri S,Kobayashi T,Barber GN,Arai H,Taguchi T
71-5300 was used in immunocytochemistry to learn the requirement of palmitoylation at the Golgi by activation of STING
Tue Jun 21 00:00:00 UTC 2016
Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis.
eLife
Wang L,Lee K,Malonis R,Sanchez I,Dynlacht BD
71-5300 was used in western blot to determine how E3 ligase tethering by PCM1 promotes ciliogenesis and controls the abundance of centrosomal KIAA0586/Talpid3
Thu May 05 00:00:00 UTC 2016
The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells.
Nature communications
Perez Bay AE,Schreiner R,Benedicto I,Paz Marzolo M,Banfelder J,Weinstein AM,Rodriguez-Boulan EJ
71-5300 was used in immunocytochemistry to define the apical recycling pathway of epithelial cells by studying the fast-recycling receptor Megalin
Mon May 16 00:00:00 UTC 2016
ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin.
eNeuro
Hara Y,Fukaya M,Hayashi K,Kawauchi T,Nakajima K,Sakagami H
715300 was used in immunocytochemistry to propose that Arf6 governs cortical neuronal migration in the intermediate zone via FIP3-dependent endosomal trafficking
Tue Oct 24 00:00:00 UTC 2017
Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.
Cell reports
Woodruff G,Reyna SM,Dunlap M,Van Der Kant R,Callender JA,Young JE,Roberts EA,Goldstein LS
715300 was used in immunocytochemistry and western blot to investigate how familial Alzheimer's disease mutations affect endocytosis
Tue Oct 11 00:00:00 UTC 2016
Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders.
Nature communications
Nakazawa T,Hashimoto R,Sakoori K,Sugaya Y,Tanimura A,Hashimotodani Y,Ohi K,Yamamori H,Yasuda Y,Umeda-Yano S,Kiyama Y,Konno K,Inoue T,Yokoyama K,Inoue T,Numata S,Ohnuma T,Iwata N,Ozaki N,Hashimoto H,Watanabe M,Manabe T,Yamamoto T,Takeda M,Kano M
71-5300 was used in western blot to characterize the role of ARHGAP33 in intracellular trafficking of TRKB and neuropsychiatric disorder pathophysiology
Wed Feb 03 00:00:00 UTC 2016
Optogenetic control of organelle transport and positioning.
Nature
van Bergeijk P,Adrian M,Hoogenraad CC,Kapitein LC
71-5300 was used in immunocytochemistry to establish a method of optical control of intracellular transport using light-sensitive heterodimerization to recruit specific cytoskeletal motor proteins to selected cargoes and test how local positioning of recycling endosomes contributes to axon
Thu Feb 05 00:00:00 UTC 2015
An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking.
Proceedings of the National Academy of Sciences of the United States of America
Schneeberger K,Vogel GF,Teunissen H,van Ommen DD,Begthel H,El Bouazzaoui L,van Vugt AH,Beekman JM,Klumperman J,Müller T,Janecke A,Gerner P,Huber LA,Hess MW,Clevers H,van Es JH,Nieuwenhuis EE,Middendorp S
71-5300 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot to study the specific role of myosin Vb gene (MYO5B) in the intestine and demonstrate that loss of MYO5B disturbs both apical and basolateral trafficking of proteins and causes microvillus inclusion disease (MVID) in mice.
Tue Oct 06 00:00:00 UTC 2015
Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Franssen EH,Zhao RR,Koseki H,Kanamarlapudi V,Hoogenraad CC,Eva R,Fawcett JW
71-5300 was used in immunocytochemistry to examine if integrin mechanisms involved in peripheral nervous system regeneration are altered in mature central nervous system axons.
Wed May 27 00:00:00 UTC 2015
SUMOylation of EHD3 Modulates Tubulation of the Endocytic Recycling Compartment.
PloS one
Cabasso O,Pekar O,Horowitz M
71-5300 was used in Immunocytochemistry to study whether EH Domain 3 undergoes SUMOylation, and examine its role in endocytic recycling.
Fri May 13 00:00:00 UTC 2016
Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis.
Annals of neurology
Moscato EH,Peng X,Jain A,Parsons TD,Dalmau J,Balice-Gordon RJ
71-5300 was used in Immunocytochemistry to support an antibody-mediated mechanism of disease pathogenesis driven by immunoglobulin-induced receptor internalisation.
Tue Jul 01 00:00:00 UTC 2014
Ttyh1 protein is expressed in glia in vitro and shows elevated expression in activated astrocytes following status epilepticus.
Neurochemical research
Wiernasz E,Kaliszewska A,Brutkowski W,Bednarczyk J,Gorniak M,Kaza B,Lukasiuk K
71-5300 was used in immunocytochemistry and immunohistochemistry to investigate the expression Ttyh1 protein in glia and activated astrocytes
Mon Dec 01 00:00:00 UTC 2014
Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes.
The Journal of biological chemistry
Bultema JJ,Boyle JA,Malenke PB,Martin FE,Dell'Angelica EC,Cheney RE,Di Pietro SM
71-5300 was used in immunocytochemistry to discover that Myosin Vc contributes to melanosome biogenesis via Rab GTPases
Fri Nov 28 00:00:00 UTC 2014
Diverse autophagosome membrane sources coalesce in recycling endosomes.
Cell
Puri C,Renna M,Bento CF,Moreau K,Rubinsztein DC
71-5300 was used in immunocytochemistry to study mATG9-ATG16L1 vesicle fusion
Thu Sep 12 00:00:00 UTC 2013
Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway.
Neuron
Das U,Scott DA,Ganguly A,Koo EH,Tang Y,Roy S
71-5300 was used in western blot to investigate the convergence of APP and BACE-.
Wed Aug 07 00:00:00 UTC 2013
Basolateral targeting and microtubule-dependent transcytosis of the aquaporin-2 water channel.
American journal of physiology. Cell physiology
Yui N,Lu HA,Chen Y,Nomura N,Bouley R,Brown D
71-5300 was used in immunohistochemistry to test if there is a transcytotic pathway of AQP2 trafficking between apical and basolateral membranes.
Tue Jan 01 00:00:00 UTC 2013
Immunocytochemical evidence of Tulp1-dependent outer segment protein transport pathways in photoreceptor cells.
Experimental eye research
Grossman GH,Watson RF,Pauer GJ,Bollinger K,Hagstrom SA
71-5300 was used in Immunohistochemistry-immunofluorescence to investigate which outer segment transport pathways in murine rod and cone photoreceptor cells are Tulp1-dependent.
Tue Nov 01 00:00:00 UTC 2011
Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells.
Molecular biology of the cell
Dukes JD,Fish L,Richardson JD,Blaikley E,Burns S,Caunt CJ,Chalmers AD,Whitley P
Thu Sep 01 00:00:00 UTC 2011
Vitamin B(6) salvage enzymes: mechanism, structure and regulation.
Biochimica et biophysica acta
di Salvo ML,Contestabile R,Safo MK
Tue Nov 01 00:00:00 UTC 2011
The Rab11 pathway is required for influenza A virus budding and filament formation.
Journal of virology
Bruce EA,Digard P,Stuart AD
71-5300 was used in immunocytochemistry and western blot to explore how the Rab11 pathway contributes to the formation of filamentous influenza A virions
Tue Jun 01 00:00:00 UTC 2010
SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment.
Nature cell biology
Traer CJ,Rutherford AC,Palmer KJ,Wassmer T,Oakley J,Attar N,Carlton JG,Kremerskothen J,Stephens DJ,Cullen PJ
71-5300 was used in immunocytochemistry to elucidate the contribution of SNX4 to endosomal sorting
Sat Dec 01 00:00:00 UTC 2007
The intracellular trafficking of the G protein-coupled receptor TPbeta depends on a direct interaction with Rab11.
The Journal of biological chemistry
Hamelin E,Thériault C,Laroche G,Parent JL
Fri Oct 28 00:00:00 UTC 2005
The intracellular trafficking of the G protein-coupled receptor TPbeta depends on a direct interaction with Rab11.
The Journal of biological chemistry
Hamelin E,Thériault C,Laroche G,Parent JL
Fri Oct 28 00:00:00 UTC 2005
The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells.
The Journal of biological chemistry
Swiatecka-Urban A,Brown A,Moreau-Marquis S,Renuka J,Coutermarsh B,Barnaby R,Karlson KH,Flotte TR,Fukuda M,Langford GM,Stanton BA
Fri Nov 04 00:00:00 UTC 2005
Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes.
Molecular biology of the cell
Wakabayashi Y,Lippincott-Schwartz J,Arias IM
Thu Jul 01 00:00:00 UTC 2004
Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes.
Molecular biology of the cell
Wakabayashi Y,Lippincott-Schwartz J,Arias IM
Thu Jul 01 00:00:00 UTC 2004
Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes.
Molecular biology of the cell
Wakabayashi Y,Lippincott-Schwartz J,Arias IM
Thu Jul 01 00:00:00 UTC 2004
Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes.
Molecular biology of the cell
Wakabayashi Y,Lippincott-Schwartz J,Arias IM
Thu Jul 01 00:00:00 UTC 2004
Local control of AMPA receptor trafficking at the postsynaptic terminal by a small GTPase of the Rab family.
The Journal of biological chemistry
Gerges NZ,Backos DS,Esteban JA
Fri Oct 15 00:00:00 UTC 2004
Rab15 mediates an early endocytic event in Chinese hamster ovary cells.
The Journal of biological chemistry
Zuk PA,Elferink LA
Fri Aug 06 00:00:00 UTC 1999
Rab15 mediates an early endocytic event in Chinese hamster ovary cells.
The Journal of biological chemistry
Zuk PA,Elferink LA
Fri Aug 06 00:00:00 UTC 1999
