Proteintech

RAB11B Polyclonal Antibody

RAB11B Antibody in Immunocytochemistry (ICC/IF)

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RAB11B Antibody (19742-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol) fixed U2OS cells using 19742-1-AP (RAB11B-Specific antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

RAB11B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RAB11B Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

19742-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:600

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Dog, Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody is specific to RAB11B. The antibody has no cross reaction to RAB11A.

Target Information

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The Late Endosomal Pathway Regulates the Ciliary Targeting of Tetraspanin Protein Peripherin 2.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Otsu W,Hsu YC,Chuang JZ,Sung CH

Wed May 01 00:00:00 UTC 2019

The Late Endosomal Pathway Regulates the Ciliary Targeting of Tetraspanin Protein Peripherin 2.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Otsu W,Hsu YC,Chuang JZ,Sung CH

Wed May 01 00:00:00 UTC 2019

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 UTC 2018

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 UTC 2018

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 UTC 2016

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 UTC 2016

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 UTC 2015

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: GTP-binding protein YPT3; RAB11B, member of RAS oncogene family; RAS oncogene family protein; Ras-related protein Rab-11B

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Gene Aliases: A730055L17Rik; H-YPT3; RAB11B; YPT3

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UniProt ID: (Human) Q15907, (Rat) O35509, (Mouse) P46638

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Entrez Gene ID: (Human) 9230, (Rat) 79434, (Mouse) 19326

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Function(s)

GTPase activity protein binding GTP binding GDP binding myosin V binding cadherin binding involved in cell-cell adhesion nucleotide binding

Process(es)

receptor recycling small GTPase mediated signal transduction melanosome transport transferrin transport insulin secretion involved in cellular response to glucose stimulus regulation of anion transport constitutive secretory pathway regulated exocytosis cellular response to acidic pH establishment of protein localization to membrane cell-cell adhesion retrograde transport, endosome to plasma membrane regulation of protein localization to cell surface regulation of endocytic recycling intracellular protein transport endocytosis Rab protein signal transduction transport protein transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RAB11B Polyclonal Antibody

RAB11B Antibody (19742-1-AP) in ICC/IF

Product Details

19742-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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