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RAB1B Polyclonal Antibody

RAB1B Antibody in Immunocytochemistry (ICC/IF)

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RAB1B Antibody (17824-1-AP) in ICC/IF

Immunofluorescent analysis of NIH/3T3 cells using 17824-1-AP (RAB1B antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

RAB1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

17824-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RAB1B Fusion Protein Ag12197 (1-201 aa encoded by BC071169)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MNPEYDYLF KLLLIGDSGV GKSCLLLRFA DDTYTESYIS TIGVDFKIRT IELDGKTIKL QIWDTAGQER FRTITSSYYR GAHGIIVVYD VTDQESYANV KQWLQEIDRY ASENVNKLLV GNKSDLTTKK VVDNTTAKEF ADSLGIPFLE TSAKNATNVE QAFMTMAAEI KKRMGPGAAS GGERPNLKID STPVKPAGGG CC (1-201 aa encoded by BC071169)

Target Information

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia.

International journal of legal medicine

Zhang M,Wang N,Guo XS,Wang LL,Wang PF,Cao ZP,Zhang FY,Wang ZW,Guan DW,Zhao R

Mon Jan 01 00:00:00 UTC 2024

Profiling of purified autophagic vesicle degradome in the maturing and aging brain.

Neuron

Kallergi E,Siva Sankar D,Matera A,Kolaxi A,Paolicelli RC,Dengjel J,Nikoletopoulou V

Wed Aug 02 00:00:00 UTC 2023

SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport.

Developmental cell

Yan R,Chen K,Wang B,Xu K

Mon Feb 28 00:00:00 UTC 2022

Fuyuan Xingnao Decoction Promotes Angiogenesis Through the Rab1/AT1R Pathway in Diabetes Mellitus Complicated With Cerebral Infarction.

Frontiers in pharmacology

Deng D,Qu Y,Sun L,Jia L,Bu J,Ye M,Chen Z,Geng Y,Zhou S,Fang B

Wed Mar 10 00:00:00 UTC 2021

Rab1b-GBF1-ARFs mediated intracellular trafficking is required for classical swine fever virus replication in swine umbilical vein endothelial cells.

Veterinary microbiology

Zhang L,Wang T,Song M,Jin M,Liu S,Guo K,Zhang Y

Wed Jul 01 00:00:00 UTC 2020

Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer.

Oncology reports

Bo H,Fan L,Gong Z,Liu Z,Shi L,Guo C,Li X,Liao Q,Zhang W,Zhou M,Xiang B,Li X,Li G,Xiong W,Zeng Z,Cao K,Zhang S,Xiong F

Mon Apr 01 00:00:00 UTC 2019

High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.

Journal of Cancer

Bo H,Fan L,Li J,Liu Z,Zhang S,Shi L,Guo C,Li X,Liao Q,Zhang W,Zhou M,Xiang B,Li X,Li G,Xiong W,Zeng Z,Xiong F,Gong Z

Thu Oct 01 00:00:00 UTC 2020

High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.

Journal of Cancer

Bo H,Fan L,Li J,Liu Z,Zhang S,Shi L,Guo C,Li X,Liao Q,Zhang W,Zhou M,Xiang B,Li X,Li G,Xiong W,Zeng Z,Xiong F,Gong Z

Thu Oct 01 00:00:00 UTC 2020

Overexpression of Rab1B and MMP9 predicts poor survival and good response to chemotherapy in patients with colorectal cancer.

Aging

Yang XZ,Cui SZ,Zeng LS,Cheng TT,Li XX,Chi J,Wang R,Zheng XF,Wang HY

Sat Mar 18 00:00:00 UTC 2017

Overexpression of Rab1B and MMP9 predicts poor survival and good response to chemotherapy in patients with colorectal cancer.

Aging

Yang XZ,Cui SZ,Zeng LS,Cheng TT,Li XX,Chi J,Wang R,Zheng XF,Wang HY

Sat Mar 18 00:00:00 UTC 2017

Rab1A is an mTORC1 activator and a colorectal oncogene.

Cancer cell

Thomas JD,Zhang YJ,Wei YH,Cho JH,Morris LE,Wang HY,Zheng XF

Mon Nov 10 00:00:00 UTC 2014

Rab1A is an mTORC1 activator and a colorectal oncogene.

Cancer cell

Thomas JD,Zhang YJ,Wei YH,Cho JH,Morris LE,Wang HY,Zheng XF

Mon Nov 10 00:00:00 UTC 2014

A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.

Nature cell biology

Reiling JH,Olive AJ,Sanyal S,Carette JE,Brummelkamp TR,Ploegh HL,Starnbach MN,Sabatini DM

Sun Dec 01 00:00:00 UTC 2013

A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.

Nature cell biology

Reiling JH,Olive AJ,Sanyal S,Carette JE,Brummelkamp TR,Ploegh HL,Starnbach MN,Sabatini DM

Sun Dec 01 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: Ras-related protein Rab-1B; small GTP-binding protein

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Gene Aliases: 1110011F09Rik; RAB1B

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UniProt ID: (Human) Q9H0U4, (Mouse) Q9D1G1

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Entrez Gene ID: (Human) 81876, (Mouse) 76308

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Function(s)

protein binding GTP binding nucleotide binding GTPase activity

Process(es)

transport intracellular protein transport ER to Golgi vesicle-mediated transport autophagy small GTPase mediated signal transduction protein transport Rab protein signal transduction positive regulation of glycoprotein metabolic process regulation of autophagosome assembly retrograde vesicle-mediated transport, Golgi to ER virion assembly COPII vesicle coating establishment of endothelial intestinal barrier

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RAB1B Polyclonal Antibody

RAB1B Antibody (17824-1-AP) in ICC/IF

Product Details

17824-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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