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Invitrogen
RAB1B Monoclonal Antibody (1673CT571.17.71)
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FIGURE: 1 / 1
RAB1B Antibody (MA5-37710) in WB
Western Blot analysis of RAB1B using the RAB1B Monoclonal Antibody (Product # MA5-37710) at a 1:4000 dilution. Lane 1: Hela whole cell lysate, Lane 2: A431 whole cell lysate, Lane 3: U-20S whole cell lysate, Lane 4: rat liver lysate, Lane 5: NIH/3T3 whole cell lysate. Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size : 22 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
MA5-37710
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1673CT571.17.71
Immunogen
recombinant protein between 1-201 amino acids from human RAB1B
Conjugate
Form
Liquid
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897634
Target Information
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RAB1B-like, member RAS oncogene family; Ras-related protein Rab-1B; small GTP-binding protein
Gene Aliases: 1110011F09Rik; RAB1B; Rab1bl
UniProt ID: (Human) Q9H0U4, (Mouse) Q9D1G1
Entrez Gene ID: (Human) 81876, (Rat) 100126191, (Mouse) 76308
intracellular protein transport
ER to Golgi vesicle-mediated transport
metabolic process
virion assembly
Rab protein signal transduction
positive regulation of glycoprotein metabolic process
regulation of autophagosome assembly
transport
autophagy
small GTPase mediated signal transduction
protein transport
retrograde vesicle-mediated transport, Golgi to ER
COPII vesicle coating
establishment of endothelial intestinal barrier
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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