Invitrogen

RAB27A Polyclonal Antibody

Advanced Verification
View all (19) RAB27A antibodies

Promotion

View available promotion(s)

Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-79904

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.5 µg/mL
- -

Immunohistochemistry (IHC)

-
- -

Immunohistochemistry (Paraffin) (IHC (P))

0.5-1 µg/mL
-

Immunohistochemistry (Frozen) (IHC (F))

0.5-1 µg/mL
-

Immunocytochemistry (ICC/IF)

0.5-1 µg/mL
-

Flow Cytometry (Flow)

1-3 µg/1x10^6 cells
-

ELISA (ELISA)

0.1-0.5 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived human RAB27A recombinant protein (Position: L98-K216).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 4mg trehalose

Contains

0.05mg sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2747019

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - WB: human Hela whole cell, human Jurkat whole cell, human MCF-7 whole cell, human HepG2 whole cell, human A549 whole cell, rat stomach tissue, rat thymus tissue, mouse thymus tissue, mouse NIH3T3 whole cell. IHC: human lung cancer tissue, human mammary cancer tissue, rat small intestine tissue, rat spleen tissue, mouse spleen tissue. Flow: K562 cell.

Target Information

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: ashen; GTP-binding protein Ram; low Mr GTP-binding protein; mutant Ras-related protein Rab-27A; Rab-27; Ram p25; Ras-related protein Rab-27A

View more View less

Gene Aliases: 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; GS2; HsT18676; RAB27; RAB27A; RAM

View more View less

UniProt ID: (Human) P51159, (Mouse) Q9ERI2, (Rat) P23640

View more View less

Entrez Gene ID: (Human) 5873, (Mouse) 11891, (Rat) 50645

View more View less

guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support