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Invitrogen
RAB29 Recombinant Rabbit Monoclonal Antibody (1H26L7)
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FIGURE: 1 / 4
RAB29 Antibody (703807) in WB
Western blot was performed using Anti-RAB29 Rabbit Recombinant Monoclonal Antibody (Product # 703807 ) and a 23 kDa band corresponding to RAB29 was observed across cell lines tested. Whole cell extract (30 µg lysate) of HeLa (Lane 1) and A-431 (Lane2) were electrophoresed using Novex® NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The blot was probed with the primary antibody (1:1000 dil... View More
Product Details
703807
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
1H26L7
Immunogen
Peptides corresponding to human RAB29 [1) aa157-aa172 2) aa185-aa198]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2848242
Product Specific Information
This antibody is predicted to react with Mouse, Rat, Bovine
Target Information
Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Rab-7-like protein 1; RAB7, member RAS oncogene family-like 1; Ras-related protein Rab-29; Ras-related protein Rab-7L1
Gene Aliases: RAB29; RAB7L; RAB7L1
UniProt ID: (Human) O14966
Entrez Gene ID: (Human) 8934
ER to Golgi vesicle-mediated transport
Golgi to endosome transport
Golgi organization
small GTPase mediated signal transduction
response to bacterium
negative regulation of neuron projection development
symbiont intracellular protein transport in host
melanosome organization
retrograde transport, plasma membrane to Golgi
retrograde transport, endosome to Golgi
protein localization to membrane
positive regulation of intracellular protein transport
regulation of neuron death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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