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Immunogen sequence: MSMEDYDFL FKIVLIGNAG VGKTCLVRRF TQGLFPPGQG ATIGVDFMIK TVEINGEKVK LQIWDTAGQE RFRSITQSYY RSANALILTY DITCEESFRC LPEWLREIEQ YASNKVITVL VGNKIDLAER REVSQQRAEE FSEAQDMYYL ETSAKESDNV EKLFLDLACR LISEARQNTL VNNVSSPLPG EGKSISYLTC CNFN (1-203 aa encoded by BC014213)
RAB30 (Ras-related protein Rab-30) encodes for small GTPases Rab which are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ras-related protein Rab-30
Gene Aliases: RAB30; Rsb30
UniProt ID: (Human) Q15771
Entrez Gene ID: (Human) 27314, (Rat) 308821
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