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Invitrogen
RAB34 Polyclonal Antibody
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FIGURE: 1 / 1
RAB34 Antibody (PA5-87817) in WB
Western blot analysis of RAB34 in extracts of various cell lines. Samples were incubated with RAB34 Polyclonal antibody (Product # PA5-87817) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-87817
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-259 of human RAB34 (NP_1141404)
Conjugate
Form
Liquid
Concentration
1.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804428
Product Specific Information
Immunogen sequence: MNILAPVRRD RVLAELPQCL RKEAALHGHK DFHPRVTCAC QEHRTGTVGF KISKVIVVGD LSVGKTCLIN RFCKDTFDKN YKATIGVDFE MERFEVLGIP FSLQLWDTAG QERFKCIAST YYRGAQAIII VFNLNDVASL EHTKQWLADA LKENDPSSVL LFLVGSKKDL STPAQYALME KDALQVAQEM KAEYWAVSSL TGENVREFFF RVAALTFEAN VLAELEKSGA RRIGDVVRIN SDDSNLYLTA SKKKPTCCP; Positive Samples: Mouse lung, Mouse brain, Mouse kidney, Mouse testis; Cellular Location: Nucleus, nucleolus
Target Information
Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region. Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and M. tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Nine amino-acid residue-repeats; rab-39; RAB34, member of RAS oncogene family; Ras-related homolog; Ras-related protein Rab-34; Ras-related protein Rab-34, isoform NARR; Ras-related protein Rab-39; Ras-related protein RAB34; Ras-related protein Rah
Gene Aliases: AI326479; NARR; RAB34; RAB39; RAH; Rah1
UniProt ID: (Human) Q9BZG1, (Mouse) Q64008, (Rat) Q5U1Y1
Entrez Gene ID: (Human) 83871, (Mouse) 19376, (Rat) 360571
small GTPase mediated signal transduction
antigen processing and presentation
lysosome localization
Golgi to plasma membrane protein transport
macropinocytosis
protein localization to plasma membrane
phagosome maturation
phagosome-lysosome fusion
transport
endocytosis
protein transport
Rab protein signal transduction
intracellular protein transport
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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