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Abnova
RAB3A Monoclonal Antibody (4H7)
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Product Details
H00005864-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
4H7
Immunogen
RAB3A (NP_002857, 122 a.a. approximately 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: TYSWDNAQVL LVGNKCDMED ERVVSSERGR QLADHLGFEF FEASAKDNIN VKQTFERLVD VICEKMSESL DTADPAVTGA KQGPQLSDQQ VPPHQDCAC
Target Information
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related protein Rab-3A
Gene Aliases: RAB3A
UniProt ID: (Human) P20336
Entrez Gene ID: (Human) 5864
respiratory system process
mitochondrion organization
small GTPase mediated signal transduction
neurotransmitter secretion
neuromuscular synaptic transmission
axonogenesis
post-embryonic development
glutamate secretion
protein transport
synaptic vesicle exocytosis
synaptic vesicle maturation
lung development
regulation of synaptic vesicle fusion to presynaptic membrane
positive regulation of ATPase activity
synaptic vesicle recycling
constitutive secretory pathway
positive regulation of exocytosis
regulation of short-term neuronal synaptic plasticity
maintenance of presynaptic active zone structure
sensory perception of touch
response to electrical stimulus
evoked neurotransmitter secretion
positive regulation of regulated secretory pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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