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Bioss
RAB3A Monoclonal Antibody (5B7)
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FIGURE: 1 / 6
RAB3A Antibody (BSM-51311M) in ICC/IF
Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized PC-12 cells labeled with RAB3A (5B7) Monoclonal Antibody (bsm-51311M) at 1/25 dilution, followed by secondary antibody (green), cytoplasmic actin staining (red), and nuclear counter stain with DAPI (blue).
Product Details
BSM-51311M
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
5B7
Immunogen
This RAB3A antibody is generated from a mouse immunized with a recombinant protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein G
Storage buffer
TBS, pH 7.4, with 40% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related protein Rab-3A; Ras-related small GTP binding protein 3A
Gene Aliases: RAB3; RAB3A
UniProt ID: (Human) P20336, (Rat) P63012, (Mouse) P63011
Entrez Gene ID: (Human) 5864, (Rat) 25531, (Mouse) 19339
respiratory system process
intracellular protein transport
vesicle docking involved in exocytosis
mitochondrion organization
neuromuscular synaptic transmission
axonogenesis
metabolic process
protein secretion
post-embryonic development
synaptic vesicle exocytosis
synaptic vesicle maturation
regulation of exocytosis
lung development
regulation of synaptic vesicle fusion to presynaptic membrane
Rab protein signal transduction
positive regulation of ATPase activity
synaptic vesicle recycling
regulation of short-term neuronal synaptic plasticity
maintenance of presynaptic active zone structure
sensory perception of touch
response to electrical stimulus
protein localization to plasma membrane
positive regulation of regulated secretory pathway
transport
exocytosis
small GTPase mediated signal transduction
protein transport
synaptic vesicle transport
evoked neurotransmitter secretion
regulation of long-term synaptic potentiation
neurotransmitter secretion
glutamate secretion
constitutive secretory pathway
positive regulation of exocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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