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Invitrogen
RAB3C Polyclonal Antibody
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FIGURE: 1 / 5
RAB3C Antibody (PA5-21963) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of RAB3C was performed in DIV9 rat E18 primary hippocampal neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: RAB3C Polyclonal Antibody (Product # PA5-21963) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-21963
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human RAB3C Recombinant protein.
Conjugate
Form
Liquid
Concentration
0.94 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153451
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, mouse brain, rat brain.
Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (81%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ras-related protein Rab-3C; small GTP-binding protein Rab3C
Gene Aliases: 2700062I01Rik; 3110015B08Rik; 3110037E15Rik; AI850886; RAB3C
UniProt ID: (Human) Q96E17, (Rat) P62824, (Mouse) P62823
Entrez Gene ID: (Human) 115827, (Rat) 171058, (Mouse) 67295
small GTPase mediated signal transduction
protein transport
regulation of exocytosis
antigen processing and presentation
intracellular protein transport
vesicle docking involved in exocytosis
metabolic process
protein secretion
synaptic vesicle exocytosis
Rab protein signal transduction
protein localization to plasma membrane
transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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