Proteintech

RAB3D Polyclonal Antibody

RAB3D Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 16

RAB3D Antibody (12320-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using (Product # 12320-1-AP) (RAB3D antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

RAB3D Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12320-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Dog, Goat, Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RAB3D Fusion Protein Ag2973 (1-219 aa encoded by BC016471)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.49 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MASAGDTQA GPRDAADQNF DYMFKLLLIG NSSVGKTSFL FRYADDSFTP AFVSTVGIDF KVKTVYRHDK RIKLQIWDTA GQERYRTITT AYYRGAMGFL LMYDIANQES FAAVQDWATQ IKTYSWDNAQ VILVGNKCDL EDERVVPAED GRRLADDLGF EFFEASAKEN INVKQVFERL VDVICEKMNE SLEPSSSSGS NGKGPAVGDA PAPQPSSCSC (1-219 aa encoded by BC016471)

Target Information

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.

Scientific reports

Gao J,Li A,Fujii S,Huang F,Nakatomi C,Nakamura I,Honda H,Kiyoshima T,Jimi E

Wed Mar 29 00:00:00 UTC 2023

RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.

Cell biology international

Yu J,Qi H,Wang Z,Zhang Z,Song E,Song W,An R

Thu Dec 01 00:00:00 UTC 2022

RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway.

Cell biology international

Yu J,Qi H,Wang Z,Zhang Z,Song E,Song W,An R

Thu Dec 01 00:00:00 UTC 2022

Porcine circovirus-like virus P1 activates pancreatic secretion pathway by interacting with CHRM3 protein.

Veterinary microbiology

Zhu J,Xiao Q,Yin L,Zhang F,Wen L,Suolang S,He K

Thu Sep 01 00:00:00 UTC 2022

Morphological and histochemical characterization of the secretory epithelium in the canine lacrimal gland.

European journal of histochemistry : EJH

Yasui T,Miyata K,Nakatsuka C,Tsukise A,Gomi H

Tue Nov 02 00:00:00 UTC 2021

Morphological and histochemical characterization of the secretory epithelium in the canine lacrimal gland.

European journal of histochemistry : EJH

Yasui T,Miyata K,Nakatsuka C,Tsukise A,Gomi H

Tue Nov 02 00:00:00 UTC 2021

Longitudinal analysis of tear cathepsin S activity levels in male non-obese diabetic mice suggests its potential as an early stage biomarker of Sjögren's Syndrome.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals

Janga SR,Shah M,Ju Y,Meng Z,Edman MC,Hamm-Alvarez SF

Fri Feb 01 00:00:00 UTC 2019

The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma.

Cancer management and research

Cao K,Fang Y,Wang H,Jiang Z,Guo L,Hu Y

Fri Jan 07 00:00:00 UTC 2022

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Gomi H,Osawa H,Uno R,Yasui T,Hosaka M,Torii S,Tsukise A

Wed Nov 01 00:00:00 UTC 2017

Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands.

European journal of histochemistry : EJH

Yasui T,Gomi H,Kitahara T,Tsukise A

Tue Aug 08 00:00:00 UTC 2017

Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands.

European journal of histochemistry : EJH

Yasui T,Gomi H,Kitahara T,Tsukise A

Tue Aug 08 00:00:00 UTC 2017

Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis.

Molecular cancer

Chang YC,Su CY,Chen MH,Chen WS,Chen CL,Hsiao M

Mon Aug 07 00:00:00 UTC 2017

Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis.

Molecular cancer

Chang YC,Su CY,Chen MH,Chen WS,Chen CL,Hsiao M

Mon Aug 07 00:00:00 UTC 2017

RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms.

Science signaling

Yang J,Wu C,Stefanescu I,Jakobsson L,Chervoneva I,Horowitz A

Tue Jul 26 00:00:00 UTC 2016

RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms.

Science signaling

Yang J,Wu C,Stefanescu I,Jakobsson L,Chervoneva I,Horowitz A

Tue Jul 26 00:00:00 UTC 2016

Fc gamma receptor IIb participates in maternal IgG trafficking of human placental endothelial cells.

International journal of molecular medicine

Ishikawa T,Takizawa T,Iwaki J,Mishima T,Ui-Tei K,Takeshita T,Matsubara S,Takizawa T

Fri May 01 00:00:00 UTC 2015

Fc gamma receptor IIb participates in maternal IgG trafficking of human placental endothelial cells.

International journal of molecular medicine

Ishikawa T,Takizawa T,Iwaki J,Mishima T,Ui-Tei K,Takeshita T,Matsubara S,Takizawa T

Fri May 01 00:00:00 UTC 2015

Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.

American journal of physiology. Gastrointestinal and liver physiology

Weis VG,Petersen CP,Mills JC,Tuma PL,Whitehead RH,Goldenring JR

Wed Oct 15 00:00:00 UTC 2014

Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.

American journal of physiology. Gastrointestinal and liver physiology

Weis VG,Petersen CP,Mills JC,Tuma PL,Whitehead RH,Goldenring JR

Wed Oct 15 00:00:00 UTC 2014

Histochemical distribution of sialic acids and antimicrobial substances in porcine carpal glands.

Archives of dermatological research

Fukui K,Yasui T,Gomi H,Sugiya H,Fujimori O,Meyer W,Tsukise A

Mon Oct 01 00:00:00 UTC 2012

Histochemical distribution of sialic acids and antimicrobial substances in porcine carpal glands.

Archives of dermatological research

Fukui K,Yasui T,Gomi H,Sugiya H,Fujimori O,Meyer W,Tsukise A

Mon Oct 01 00:00:00 UTC 2012

Histochemical localization of sialic acids and antimicrobial substances in eccrine glands of porcine snout skin.

European journal of histochemistry : EJH

Fukui K,Yasui T,Gomi H,Sugiya H,Fujimori O,Meyer W,Tsukise A

Thu Feb 09 00:00:00 UTC 2012

Histochemical localization of sialic acids and antimicrobial substances in eccrine glands of porcine snout skin.

European journal of histochemistry : EJH

Fukui K,Yasui T,Gomi H,Sugiya H,Fujimori O,Meyer W,Tsukise A

Thu Feb 09 00:00:00 UTC 2012

Accumulation of secretory vesicles in the lacrimal gland epithelia is related to non-Sjögren's type dry eye in visual display terminal users.

PloS one

Kamoi M,Ogawa Y,Nakamura S,Dogru M,Nagai T,Obata H,Ito M,Kaido M,Kawakita T,Okada Y,Kawakami Y,Shimmura S,Tsubota K

Tue Jan 22 00:00:00 UTC 2013

Accumulation of secretory vesicles in the lacrimal gland epithelia is related to non-Sjögren's type dry eye in visual display terminal users.

PloS one

Kamoi M,Ogawa Y,Nakamura S,Dogru M,Nagai T,Obata H,Ito M,Kaido M,Kawakita T,Okada Y,Kawakami Y,Shimmura S,Tsubota K

Tue Jan 22 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: glioblastoma overexpressed; GTP-binding protein Rab-3D; Rab3D upregulated with myeloid differentiation; Ras-related protein Rab-3D

View more View less

Gene Aliases: C130057E11Rik; D2-2; GOV; RAB16; RAB3D; RAD3D

View more View less

UniProt ID: (Human) O95716, (Mouse) P35276, (Rat) Q63942

View more View less

Entrez Gene ID: (Human) 9545, (Mouse) 19340, (Rat) 140665

View more View less

Function(s)

GTPase activity GTP binding myosin V binding GTPase binding nucleotide binding protein binding GDP binding

Process(es)

exocytosis small GTPase mediated signal transduction protein transport peptidyl-cysteine methylation bone resorption positive regulation of regulated secretory pathway transport intracellular protein transport vesicle docking involved in exocytosis protein secretion synaptic vesicle exocytosis regulation of exocytosis Rab protein signal transduction protein localization to plasma membrane

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

RAB3D Polyclonal Antibody

RAB3D Antibody (12320-1-AP) in IHC (P)

Product Details

12320-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!