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Proteintech
RAB3GAP2 Monoclonal Antibody (3A4A1)
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Product Details
66648-1-IG
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
3A4A1
Immunogen
RAB3GAP2 Fusion Protein Ag20254 (1-204 aa encoded by BC146760)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MACSIVQFC YFQDLQAARD FLFPHLREEI LSGALRRDPS KSTDWEDDGW GAWEENEPQE PEEEGNTCKT QKTSWLQDCV LSLSPTNDLM VIAREQKAVF LVPKWKYSDK GKEEMQFAVG WSGSLNVEEG ECVTSALCIP LASQKRSSTG RPDWTCIVVG FTSGYVRFYT ENGVLLLAQL LNEDPVLQLK CRTYEIPRHP GVTEQ (1-204 aa encoded by BC146760)
Target Information
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RAB3 GTPase activating protein subunit 2 (non-catalytic); Rab3 GTPase-activating protein 150 kDa subunit; Rab3 GTPase-activating protein non-catalytic subunit; Rab3-GAP p150; Rab3-GAP regulatory subunit; Rab3-GAP150; RGAP-iso
Gene Aliases: KIAA0839; p150; RAB3-GAP150; RAB3GAP150; RAB3GAP2; SPG69; WARBM2
UniProt ID: (Human) Q9H2M9
Entrez Gene ID: (Human) 25782
intracellular protein transport
regulation of GTPase activity
positive regulation of GTPase activity
establishment of protein localization to endoplasmic reticulum membrane
positive regulation of protein lipidation
positive regulation of endoplasmic reticulum tubular network organization
positive regulation of autophagosome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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