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Invitrogen
RAB6A Polyclonal Antibody
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FIGURE: 1 / 1
RAB6A Antibody (PA5-88341) in WB
Western blot analysis of RAB6A in mouse brain. Samples were incubated with RAB6A Polyclonal antibody (Product # PA5-88341) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-88341
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A (NP_0028602)
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804842
Product Specific Information
Immunogen sequence: MSTGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TIRLQLWDTA GQERFRSLIP SYIRDSAAAV VVYDITNVNS FQQTTKWIDD VRTERGSDVI IMLVGNKTDL ADKRQVSIEE GERKAKELNV MFIETSAKAG YNVKQLFRRV AAALPGMEST QDRSREDMID IKLEKPQEQP; Positive Samples: Mouse brain; Cellular Location: Golgi apparatus, Golgi apparatus membrane, Lipid-anchor
Target Information
Rab proteins are also an integral part of endocytic pathways. Rab 6A is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it regulates retrograde transport from the late endosomes via the Golgi to endoplasmic reticulum (ER) pathway. Three isoforms exist due to alternative splicing events, namely the ubiquitously expressed isoforms Rab 6A' and Rab 6A, and the brain-specific isoform Rab 6B.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Rab-6; RAB6, member RAS oncogene family; Ras-related protein Rab-6A
Gene Aliases: 2610028L11Rik; AA419671; MNCb-1660; Rab6; Rab6a
UniProt ID: (Mouse) P35279
Entrez Gene ID: (Mouse) 19346
protein targeting to Golgi
transport
intracellular protein transport
retrograde vesicle-mediated transport, Golgi to ER
intra-Golgi vesicle-mediated transport
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
peptidyl-cysteine methylation
antigen processing and presentation
Rab protein signal transduction
positive regulation of ATPase activity
protein localization to Golgi apparatus
early endosome to Golgi transport
retrograde transport, endosome to Golgi
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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