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Proteintech
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Immunogen sequence: MKQLPVLEP GDKPRKATWY TLTVPGDSPC ARVGHSCSYL PPVGNAKRGK VFIVGGANPN GSFSDVHTMD LGKHQWDLDT CKGLLPRYEH ASFIPSCTPD RIWVFGGANQ SGNRNCLQVL NPETRTWTTP EVTSPPPSPR TFHTSSAAIG NQLYVFGGGE RGAQPVQDTK LHVFDANTLT WSQPETLGNP PSPRHGHVMV AAGTKLFIHG GLAGDRFYDD LHCIDISDMK WQKLNPTGAA PAGCAAHSAV AMGKHVYIFG GMTPAGALDT MYQYHTEEQH WTLLKFDTLL PPGRLDHSMC IIPWPVTCAS EKEDSNSLTL NHEAEKEDSA DKVMSHSGDS HEESQTATLL CLVFGGMNTE GEIYDDCIVT VVD (1-372 aa encoded by BC065725)
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 40 kDa Rab9 effector protein; p40; Rab9 effector p40; Rab9 effector protein with kelch motifs
Gene Aliases: bA65N13.1; p40; RAB9P40; RABEPK
UniProt ID: (Human) Q7Z6M1
Entrez Gene ID: (Human) 10244
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