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Abnova
RAD17 Polyclonal Antibody, MaxPab™
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Product Details
H00005884-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAD17 (NP_579919.1, 1 a.a. approximately 584 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MNQHELAVHK KKIEEVETWL KAQVLERQPK QGGSILLITG PPGCGKTTTL KILSKEHGIQ VQEWINPVLP DFQKDDFKGM FNTESSFHMF PYQSQIAVFK EFLLRATKYN KLQMLGDDLR TDKKIILVED LPNQFYRDSH TLHEVLRKYV RIGRCPLIFI ISDSLSGDNN QRLLFPKEIQ EECSISNISF NPVAPTIMMK FLNRIVTIEA NKNGGKITVP DKTSLELLCQ GCSGDIRSAI NSLQFSSSKG ENNLRPRKKG MSLKSDAVLS KSKRRKKPDR VFENQEVQAI GGKDVSLFLF RALGKILYCK RASLTELDSP RLPSHLSEYE RDTLLVEPEE VVEMSHMPGD LFNLYLHQNY IDFFMEIDDI VRASEFLSFA DILSGDWNTR SLLREYSTSI ATRGVMHSNK ARGYAHCQGG GSSFRPLHKP QWFLINKKYR ENCLAAKALF PDFCLPALCL QTQLLPYLAL LTIPMRNQAQ ISFIQDIGRL PLKRHFGRLK MEALTDREHG MIDPDSGDEA QLNGGHSAEE SLGEPTQATV PETWSLPLSQ NSASELPASQ PQPFSAQGDM EENIIIEDYE SDGT
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell cycle checkpoint protein (RAD17); Cell cycle checkpoint protein RAD17; FLJ41520; hRad17; RAD1 homolog; RAD17 (Ser647); RAD17 homolog; Rad17 like protein; Rad17-like protein; RF-C activator 1 homolog; RF-C/activator 1 homolog
Gene Aliases: CCYC; HRAD17; R24L; RAD17; RAD17SP; RAD24
UniProt ID: (Human) O75943
Entrez Gene ID: (Human) 5884
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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