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Invitrogen
RAD17 Polyclonal Antibody
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Product Details
PA1-4131
Product Specifications
Species Reactivity
Yeast
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues S(10) T K R S L K K K K I R K I(23) of the 75 kDa S. pombe RAD17.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_560820
Product Specific Information
PA1-4131 detects yeast RAD17.
PA1-4131 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~75 kDa protein representing RAD17 in yeast.
The PA1- 4131 immunogen is a synthetic peptide corresponding to residues S(10) T K R S L K K K K I R K I(23) of the 75 kDa S. pombe RAD17.
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; RAD17 (Ser647); Rad17 like protein; Rad17p
Gene Aliases: RAD17; YOR368W
UniProt ID: (Baker's yeast) P48581
Entrez Gene ID: (Baker's yeast) 854550
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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