Proteintech

RAD51AP1 Polyclonal Antibody

RAD51AP1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

RAD51AP1 Antibody (11255-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA ) fixed HeLa cells using 11255-1-AP (RAD51AP1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

11255-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 7 publications 7 publications

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RAD51AP1 Fusion Protein Ag1781 (1-352 aa encoded by BC016330)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.16 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MVRPVRHKK PVNYSQFDHS DSDDDFVSAT VPLNKKSRTA PKELKQDKPK PNLNNLRKEE IPVQEKTPKK RLPEGTFSIP ASAVPCTKMA LDDKLYQRDL EVALALSVKE LPTVTTNVQN SQDKSIEKHG SSKIETMNKS PHISNCSVAS DYLDLDKITV EDDVGGVQGK RKAASKAAAQ QRKILLEGSD GDSANDTEPD FAPGEDSEDD SDFCESEDND EDFSMRKSKV KEIKKKEVKV KSPVEKKEKK SKSKCNALVT SVDSAPAAVK SESQSLPKKV SLSSDTTRKP LEIRSPSAES KKPKWVPPAA SGGSRSSSSP LVVVSVKSPN QSLRLGLSRL ARVKPLHPNA TST (1-352 aa encoded by BC016330)

Target Information

May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis.

Frontiers in genetics

Liu R,Zhu G,Li M,Cao P,Li X,Zhang X,Huang H,Song Z,Chen J

Tue Dec 06 00:00:00 UTC 2022

METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.

International journal of oncology

Li M,Xia M,Zhang Z,Tan Y,Li E,Guo Z,Fang M,Zhu Y,Hu Z

Thu Sep 01 00:00:00 UTC 2022

TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.

Molecular cell

Yadav T,Zhang JM,Ouyang J,Leung W,Simoneau A,Zou L

Thu Nov 03 00:00:00 UTC 2022

Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.

Cancer research

Cheng L,Zhou S,Zhou S,Shi K,Cheng Y,Cai MC,Ye K,Lin L,Zhang Z,Jia C,Xiang H,Zang J,Zhang M,Yin X,Li Y,Di W,Zhuang G,Tan L

Tue Oct 04 00:00:00 UTC 2022

The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes.

Journal of cellular biochemistry

Ishikura S,Nagai M,Tsunoda T,Nishi K,Tanaka Y,Koyanagi M,Shirasawa S

Tue Jun 01 00:00:00 UTC 2021

BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.

Oncogene

Ni M,Li J,Zhao H,Xu F,Cheng J,Yu M,Ke G,Wu X

Thu Apr 01 00:00:00 UTC 2021

RNA transcripts stimulate homologous recombination by forming DR-loops.

Nature

Ouyang J,Yadav T,Zhang JM,Yang H,Rheinbay E,Guo H,Haber DA,Lan L,Zou L

Tue Jun 01 00:00:00 UTC 2021

RNA transcripts stimulate homologous recombination by forming DR-loops.

Nature

Ouyang J,Yadav T,Zhang JM,Yang H,Rheinbay E,Guo H,Haber DA,Lan L,Zou L

Tue Jun 01 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: HsRAD51AP1; RAB22; RAD51-associated protein 1; RAD51-interacting protein; RAD51AP1

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Gene Aliases: 2510006L10Rik; PIR51; RAB22; RAD51AP1

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UniProt ID: (Human) Q96B01, (Mouse) Q8C551

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Entrez Gene ID: (Human) 10635, (Rat) 689055, (Mouse) 19362

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Function(s)

double-stranded DNA binding single-stranded DNA binding RNA binding protein binding DNA binding

Process(es)

DNA repair DNA recombination regulation of double-strand break repair via homologous recombination cellular response to ionizing radiation cellular response to DNA damage stimulus double-strand break repair via homologous recombination DNA synthesis involved in DNA repair strand displacement interstrand cross-link repair

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RAD51AP1 Polyclonal Antibody

RAD51AP1 Antibody (11255-1-AP) in ICC/IF

Product Details

11255-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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