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Proteintech
RAE1 Polyclonal Antibody
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Product Details
20491-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAE1 Fusion Protein Ag12102 (1-368 aa encoded by BC103754)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSLFGTTSG FGTSGTSMFG SATTDNHNPM KDIEVTSSPD DSIGCLSFSP PTLPGNFLIA GSWANDVRCW EVQDSGQTIP KAQQMHTGPV LDVCWSDDGS KVFTASCDKT AKMWDLSSNQ AIQIAQHDAP VKTIHWIKAP NYSCVMTGSW DKTLKFWDTR SSNPMMVLQL PERCYCADVI YPMAVVATAE RGLIVYQLEN QPSEFRRIES PLKHQHRCVA IFKDKQNKPT GFALGSIEGR VAIHYINPPN PAKDNFTFKC HRSNGTNTSA PQDIYAVNGI AFHPVHGTLA TVGSDGRFSF WDKDARTKLK TSEQLDQPIS ACCFNHNGNI FAYASSYDWS KGHEFYNPQK KNYIFLRNAA EELKPRNKK (1-368 aa encoded by BC103754 )
Target Information
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ30608; HGNC:9828; homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer); MGC117333; MGC126076; MGC126077; migration-inducing gene 14; mRNA export factor RAE1; mRNA export protein; mRNA-associated protein MRNP 41; mRNA-binding protein, 41-kD; OTTHUMP00000166110; Rae1 protein homolog; RAE1 RNA export 1 homolog; RP4-800J21.2
Gene Aliases: dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41; RAE1
UniProt ID: (Human) P78406
Entrez Gene ID: (Human) 8480
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
cellular response to organic cyclic compound
intracellular transport of virus
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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