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RAE1 gamma Antibody (PA5-47078) in IHC (F)
Immunohistochemical analysis of RAE1 gamma in immersion fixed frozen sections of mouse embryo (13 d.p.c.). Samples were incubated in RAE1 gamma polyclonal antibody (Product # PA5-47078) using a dilution of 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to axons of primary... View More
Product Details
PA5-47078
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Rae-1 gamma Leu29-Ser231
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610488
Product Specific Information
This antibody detects mouse Rae-1 gamma as well as mouse Rae-1 alpha, 1 beta, 1 gamma and 1 epsilon in direct ELISAs and Western blots.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; mRNA export factor; mRNA export protein; MRNP41; RAE-1-gamma; Retinoic acid early-inducible protein 1-gamma; RP4-800J21.2
Gene Aliases: RAE-1gamma; Raet1c
UniProt ID: (Mouse) O08604
Entrez Gene ID: (Mouse) 19370
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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