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Invitrogen
RAG1 Monoclonal Antibody (1D9)
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Product Details
MA5-17163
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D9
Immunogen
Purified recombinant fragment of human RAG1 (amino acids: 818-868) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538634
Product Specific Information
MA5-17163 targets RAG1 in indirect ELISA and WB applications and shows reactivity with Human samples.
The MA5-17163 immunogen is purified recombinant fragment of human RAG1 (amino acids: 818-868) expressed in E. Coli.
MA5-17163 detects RAG1 which has a predicted molecular weight of approximately 119kDa.
Target Information
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC43321; RAG-1; RAG-1 Antibody; recombination activating gene 1 Antibody; recombination activating protein 1; RING finger protein 74; RNF74 Antibody; V(D)J recombination-activating protein 1
Gene Aliases: RAG-1; RAG1; RNF74
UniProt ID: (Human) P15918
Entrez Gene ID: (Human) 5896
adaptive immune response
pre-B cell allelic exclusion
DNA recombination
immune response
histone monoubiquitination
B cell differentiation
T cell differentiation in thymus
V(D)J recombination
T cell homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of T cell differentiation
thymus development
protein autoubiquitination
negative regulation of thymocyte apoptotic process
nucleic acid phosphodiester bond hydrolysis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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